Exam 1 Nura 221 COX inhibitors and
Opioids
COX - answercyclo-oxygenase
an important enzyme in the synthesis of prostaglandin
Cox is found in all tissues and helps regulate many processes
COX inhibitors - answerNSAIDs (Non-Steroidal Anti-Inflammatory Medications)
and selective COX2 inhibitors
...
3 primary functions of NSAIDS - answer✔✔•Suppression of inflammation
•Relief of pain (analgesic)
•Reduction of fever (anti-pyretic)
Two types of Cox inhibitors - answer✔✔specific and non-specific
What are non-specific cox inhibitors? - answer✔✔NSAID that blocks the action of cox1 and
cox2
also called First-generation
What are specific cox inhibitors? - answer✔✔NSAIDs that mostly block cox2
also called Second Generation
What will non-specific (first gen) COX inhibitors do? - answer✔✔Blockage of Cox2
•Suppression of inflammation
•Suppression of fever
•Suppression of pain
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