PMY 302 Lec 1 Exam Questions With
Revised Answers.
Drug - answer✔✔Any agent that affects the living process, including chemicals that mimic or
antagonize endogenous substances
Dose - answer✔✔Amount of medication administered at a single time
Response - answer✔✔Effect of a drug on the body, including both intended and unintended
effects
Therapeutic Response - answer✔✔Is a response you are looking for the drug to do. In heroin's
case it's used for pain relief (very good at that)
Adverse Response - answer✔✔Are side effects (e.g. heroin has many). Independence, rolling
into drug abuse. Respiratory depression (life threatening)
Toxic Response - answer✔✔Toxic leukoencephalopathy (holes in your brain) Produces vacuoles
resulting in holes in the brain (toxic response of heroin).
Idiosyncratic Responses - answer✔✔Has to do with individual's hypersensitivity.
Allergic Reaction - answer✔✔Nerve occurs on first response (because allergic reaction is a
response built up by immune system, so upon first exposure to drug it does not have adverse
response. but immune response under the radar decides that its foreign and builds up resources to
combate foriegn object in body. So in sunsequent eposure its allergic reaction)
Idiosyncratic Drug Response - answer✔✔Can occur on first exposure to medication only occurs
in succpetible individuals and how to identiy these individuals not very clear but it's presumed to
be genetic or metabolic abnormality and it's really unknown. Does not occur in most patients,
does not generally involve immune response. Very unpredictable occurence.
Anaphylaxis - answer✔✔Can cause respiratory constriction, rashes, etc...these can all be
mediated through mast cells and other components of immune system but just because they go
through immmune system doesn't mean its an allergic reaction. Allergic reaction must start with
antibodies that have been rasied by body agains't particaly antigens that would then mediate
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