Exam (elaborations)
PHCY 402- Tetracyclines Exam Latest Update
- Course
- Institution
PHCY 402- Tetracyclines Exam Latest Update ...
[Show more]
Content preview
PHCY 402- Tetracyclines ExamLatest Update
Tetracyclines are used against broad Gram +/- _____ - Answer parasites
Tetracyclines are (static/cidal) - Answer static
Tetracycline structures are made up of ____ rings - Answer four
Tetracyclines (reversibly/irreversibly) binds the the __ site of the ____ ribosome - Answer
reversibly; A; 30S
T/F: tetracyclines are the only drugs that bind 30S subunit - Answer false
(aminoglycosides also)
Tetracycline prefer which type of environment: acidic, basic, or neutral? - Answer acidic
Tetracyclines can undergo a process called ____ where they bind with metal cations and
become inactive - Answer chelation
two ways tetracyclines would get into G+ - Answer passive diffusion & active transport
How do hydrophilic tetracyclines get into G- - Answer pores
How do lipophilic tetracyclines get into G- - Answer diffuse through membrane
resistance that causes tetracycline to be dislodged from its binding site - Answer Tet(O)
major resistance associated with tetracyclines - Answer efflux
T/F: tetracyclines can be given to pregnant women - Answer false (crosses the placenta;
also excreted in breast milk)
tetracyclines have (good/bad) CNS penetration - Answer bad (would NOT be used for
meningitis, etc)
Tetracyclines cause problems with teeth because they bind ______ and cause
discoloration - Answer calcium
What type of tetracycline product would cause Fanconi-like syndrome? - Answer
expired (out of date)
Two things that happen to expired tetracyclines that lead to renal toxicity - Answer
dehydration & epimerization
tetracycline side effect due to accumulation in the skin - Answer phototoxicity (abnormal
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Zayla. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
81113 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now
