Exam (elaborations)
NAPLEX PRACTICE QUESTIONS -CARDIOVASCULAR CONDITIONS QUESTIONS AND ANSWERS WITH SOLUTIONS 2024
NAPLEX PRACTICE QUESTIONS -CARDIOVASCULAR CONDITIONS QUESTIONS AND ANSWERS WITH SOLUTIONS 2024
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NAPLEX PRACTICE QUESTIONS -
CARDIOVASCULAR CONDITIONS
QUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
AllAofAtheAfollowingAareAantiplateletAagentsAthatAcanAbeAusedAinAtheAtreatmentAofAanAacuteAcoronaryAsynd
romeAEXCEPT:
A.AClopidogrel
B.ADalteparin
C.AEptifibatide
D.ATicagrelor
E.AAspirinA-AANSWERAB.ADalteparin
Aspirin,AP2Y12AinhibitorsAandAglycoproteinAIIb/IIIaAreceptorAantagonistsAcanAbeAgloballyAcalledA"antiplatel
etAagents"AbasedAonAtheirAmechanismsAofAaction.ADalteparinAisAanAanticoagulant.
DLAisAaA77-year-
oldAmaleA(6'3",A315Apounds)AwhoApresentsAtoAtheAemergencyAdepartmentAwithAaASTEMI.AHeAwasAgivenAas
pirinA325AmgAinAtheAfieldAandAwasAstartedAonAaAnitroglycerinAdripAatA100Amcg/min.AHisAoxygenAsaturationAi
sA94%AandAheAhasAreceivedAmorphineAsulfateA2AmgAIVA×A2AandAmetoprololA5AmgAIAinAtheApastA30Aminutes.A
HisAbloodApressureAisA164/101,AHRAisA95Abpm,AandAhisArespiratoryArateAisA22Abpm.AWhichAofAtheAfollowingA
medicationsAshouldANOTAbeAgivenAtoAtheApatientAdueAtoAincreasedAmortality?
A.ANifedipineAimmediate-release
B.ATorsemide
C.ACandesartan
D.ADiltiazemAextended-release
E.AEnalaprilA-AANSWERAA.ANifedipineAimmediate-release
Immediate-releaseAnifedipineAisAassociatedAwithAincreasedAmortalityAwhenAusedAinAtheAacuteAsetting.
,WhatAisAtheAprimaryAreasonAforAusingAaspirinAinAaApatientAwithAchestApain?
A.AInhibitAplateletAaggregation
B.AProvideAmoderateAdegreeAofAanalgesia
C.AIncreaseAmortalityAinApatientsAwithASTEMI
D.APreventAflushing
E.ABreakAdownAtheAclotA-AANSWERAA.AInhibitAplateletAaggregation
AspirinAinhibitsAplateletAaggregation,AstabilizesAplaqueAandAhelpsAtoAarrestAthrombusAformation.
AspirinAdoesAnotAbreakAdownAtheAexistingAclot,AbutAratherApreventsAitAfromAenlargingAandAprogressing.AAs
pirinAprovidesAveryAmildAanalgesiaAandAisAnotAusedAforAanalgesiaAinApatientsAwithAchestApain.
AApharmacistAcoveringAtheAemergencyAdepartmentAreceivesAanAorderAforAtissueAplasminogenAactivatorA(t
PA)A15AmgAIVAbolus,A50AmgAoverA30Amin,AthenA35AmgAoverA1Ahour.ATotalAdoseA=A100Amg.AWhatAdrugAisAbei
ngAordered?
A.AAbciximab
B.AAlteplase
C.AEpitifibatide
D.ATenecteplase
E.ATirofibanA-AANSWERAB.ALateAplease
AlteplaseA(Activase)AisArecombinantAtissueAplasminogenAactivatorA(rtPAAorAsimpleA"(PA").
CorrectAdosingAisAcriticalAdueAtoAbleedingArisk.ATheAacceleratedAinfusionAdosingAforASTEMIAdiffersAfromAthe
ArecommendedAdoseAforAacuteAischemicAstrokeA(seeAStrokeAchapter).
AHAisAbeingAdischargedAfromAtheAhospitalAafterAaAmyocardialAinfarction.ATwoAbare-
metalAstentsAwereAplacedAyesterday.AUponAdischarge,AheAwillAcontinueAtakingAhisAPrasugrelAtherapyAwhic
hAwasAstartedAyesterday.AWhatAisAtheAminimumAperiodAofAtimeAthatAAHAwillAneedAtoAtakeAPrasugrel?
,A.A6Amonths
B.A1Ayear
C.A2Ayears
D.A3Ayears
E.AIndefinitelyA-AANSWERAB.A1Ayear
AfterAanAMI,ApatientsAshouldAreceiveAaspirinAandAaAP2YA12AinhibitorAforAaAminimumAofA12Amonths.
TheAminimumArecommendationAisAtheAsameAforApatientsAmanagedAmedicallyAorAforAthoseAstented.
WhichAofAtheAfollowingAmedicationsAshouldAbeAavoidedAinAaApatientApresentingAwithAACS?
A.AMetoprolol
B.ALisinopril
C.ACelecoxib
D.AAspirin
E.AEnoxaparinA-AANSWERAC.ACelecoxib
NSAIDsA(exceptAaspirin),AregardlessAofACOXAselectivity,AshouldAbeAavoidedAinApatientsAwithAACS.AIfAsaferAag
entsA(acetaminophen,Atramadol,AsmallAdosesAofAopioids)AareAnotAeffective,AnaproxenAisAgenerallyAconside
redAtoAhaveAtheAlowestAcardiovascularAriskA(butAthereAisAstillArisk).
WhichAofAtheAfollowingAareAlikelyAsigns/symptomsAofAaAheartAattack?A(SelectAALLAthatAapply.)
A.AChestApainAorApressureAthatAlastsAmoreAthanAaAfewAminutes
B.AShortnessAofAbreath
C.AIncontinence
D.ASweating
E.ASeizure
F.ARadiatingApainA-AANSWERAA.AChestApainAorApressureAthatAlastsAmoreAthanAaAfewAminutes
, B.AShortnessAofAbreath
D.ASweating
F.ARadiatingApain
ManyAmyocardialAinfarctionsAinvolveAchestAdiscomfortAthatAlastsA10AminutesAorAmore,AorAthatAgoesAawayA
andAcomesAback.ATheApainAcanAradiateAforAextend)AtoAoneAorAbothAamAtheAbackAneck,AjawAorAstomachAand
AmayAbeAdesoribedAasA"squeezing"AorA'ressure",AShortessAofAbreathA(dyspnea)AandAsweatingA(diaphoresis)
AmayAalsoAoccur.
SRAisAaA61-year-
oldAfemaleA(5'3",A115Apounds)AwhoApresentsAtoAtheAemergencyAdepartmentAwithAaANSTEMI.AHerApastAme
dicalAhistoryAisAsignificantAforAdiabetes,Ahypertension,AmultipleATIAsAandAaAhipAfracture.ASheAwasAgivenAas
pirinA325AmgAinAtheAfieldAandAwasAstartedAonAaAnitroglycerinAdripAatA50Amcg/min.AHerAoxygenAsaturationAi
sA93%AandAsheAhasAreceivedAmorphineAsulfateA1AmgAIVAxA1AinAtheApastA30Aminutes.ASheAisAtransferredAtoAt
heAcardiacAcatheterizationAlaboratoryAandAangiographyAconfirmedAanA85%AblockageAofAherAleftAmarginalAa
rtery.ATheAcardiacAinterventionalistAwantsAtoAstartAaAP2Y12AinhibitorApriorAtoAtheAPCI.AWhichAmedicationAis
Aappropriate?
A.AActivase
B.AEffient
C.ALovenox
D.ABrilinta
E.ATNKaseA-AANSWERAD.ABrilinta
ThisApatientAhasAaAcontraindicationAtoAtheAuseAofAEffientA(historyAofATIA/stroke).AActivase,ATNKaseAandALov
enoxAdoAnotAworkAbyAP2YA12Ainhibition.
AApatientApresentingAwithAchestApainAunderwentAaAprocedureAtoAopenAaAcoronaryAartery,AThisAwasAdoneA
byAinflatingAaAsmallAballoonAinsideAtheAarteryAandAthenAplacingAaAstentAafterwardAtoAkeepAtheAarteryAopen
.AWhatAprocedureAdidAthisApatientAhaveAdone?
A.ACABG
B.AComputedAtomography