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APHA NAPLEX 2024 STUDY GUIDE QUESTIONS AND ANSWERS WITH SOLUTIONS 2024
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APHA NAPLEX 2024 STUDY GUIDE QUESTIONS AND ANSWERS WITH SOLUTIONS 2024
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APHA NAPLEX 2024 STUDY GUIDEQUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
VolumeIofIDistributionI-IANSWERIamountIofIdrugIinItheIbody/concentrationIofIdrugIinIplasma
Lipophilicity--I-IANSWERIhighIlipophilicityIincreasesIpassageIintoItissues
MolecularIweight---I-IANSWERIlowImolecularIweightIallowsIdrugsItoIpassImembranesIeasier
Ionization--I-IANSWERIun-ionizedIdrugsIhaveIincreasedIdistribution
ProteinIbinding--I-IANSWERIlowIproteinIbindingIinIbloodIisIimportantIforIincreasedIdistribution
Membranes--I-IANSWERIincreasedImembraneIpermeabilityIincreasesIdistributinoIintoItissues
InDucers--I-IANSWERIDecreaseIdrugIlevels:IprodrugsIinducersIincreaseIlevelsIofItheIactiveIform
Ultra-metabolizersIhaveIsameIeffectIonIdrugIlevels
INhibitors--I-IANSWERIINcreaseIdrugIlevels:IprodrugsIinhibitorsIdecreaseIlevelsIofIactiveIform
PoorImetabolizersIhaveIsameIeffect
ClearanceI-IANSWERIkeIXIVd
CommonIInducersI-IANSWERISUPERICOPS
Smoking,IU,IPhenytoin,IE,IRifampin,ICarbamazepine,IOxcarbezepine,IPhenobarbital,ISt.IJohn'sIWort
CommonIInhibitorsI-IANSWERICAMPAIGN
Cimetidine,IAzoles,IMacrolides,IProteaseIinhibitors,IAmiodarone,II,IGrapefruit,INon-DHPICCB
,Half-LifeI-IANSWERI0.693/ke--itItakesI5IhalfIlivesItoIreachIsteadyIstate
IVIloadingIdoseI-IANSWERIdesiredIconcentrationIXIVd/F
Non-IVIloadingIdoseI-IANSWERImaintenanceIdoseIXIRaI(accumulationIfactor)
WhatIareItheI5IGsIandIwhatIdoItheyIincreaseItheIriskIof?I-
IANSWERIGarlic,IGinkgo,IGinger,IGinseng,IGlucosamine--increaseIbleedingIrisk
PercentageIorIratioIstrengthI-
IANSWERIJustItakeIwhatIeverIyouIhaveIandIthenIdoI100/thatInumberItoIgetItheIother
PPMIfromIpercentageIstrengthI-IANSWERIMoveItheIdecimalIleftI4Ispots
PercentageIstrengthIfromIPPMI-IANSWERIMoveItheIdecimalIrightI4Ispots
SpecificIgravityI-IANSWERIg/mL
mOsmol/LI-IANSWERIweightIofIsubstance/MWIXInumberIofIparticlesIXI1000
molsI-IANSWERIg/MW
mmolsI-IANSWERImg/MW
mEqI-IANSWERImgIXIvalence/MW
DextroseI-IANSWERI3.4Ikcal
, ProteinI-IANSWERI4Ikcal
FatI10%I-IANSWERI1.1Ikcal
FatI20%I-IANSWERI2Ikcal
DailyIFluidIGoalI-IANSWERIIfIweightIisI>I20Ikg:I1500ImLI+I20Iml(weightI-20)
GoodIindicatorIofIdehydrationI-IANSWERItheIBUN:SCr>20:1
CorrectedICalciumI-IANSWERIMeasureIcalciumI+I0.8(4-albumin)
CalciumIandIphosphateIreplacementI-
IANSWERIAddIphosphateIthenIcalcium,IuseIcalciumIgluconateIversusIcalciumIchloride,IthemIaddedItogetherI
shouldInotIexceedI45ImEq/L
BMII-IANSWERIlb/inches^2IX703
IBWIfemalesI-IANSWERI45.5+2.3(inchesIoverIfiveIft)
AdjBWI-IANSWERIIBW+0.4(actualIBW-IBW)
CrCLI-IANSWERI140-ageIXIwt/72IXISCr....XI0.85IifIfemale
AnionIGapI-IANSWERINa-Cl-HCO3
ANCI-IANSWERIWBCIXI(segI+Ibands)/100
FurosemideItoIbumetanideI-IANSWERI40:1
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