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Exam (elaborations)

AUBF-CSF part 2

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  • September 8, 2024
  • 34
  • 2024/2025
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97 Multiple choice questions

Term 1 of 97
The rapid plasma regain (RPR) test

What is the major beta globulin seen in csf?

- These cells originate primarily from lung, breast, renal, and gastrointestinal malignancies.

What is the reagent used in nogochi test and what is the result if positive?

This test is not recommended because it is less sensitive than the VDRL.

Definition 2 of 97
A reagent used in Turbidimetry that precipitates albumin only unless combined with Na2SO4.

Dietary intake (k+)

Trichloroacetic acid (tca)

Multiple sclerosis (ms)

Sulfosalicylic acid (SSA)

Definition 3 of 97
In Chemistry test why does Normal values of blood differs?

Virus is spread by the fecal-oral route


Demyelination

Detection of myelin basic protein


Because of the blood-brain barrier

,Definition 4 of 97
When proteins (i.e. immunoglobulins) enter the CSF this means that the ______ is damaged.

Neurotransmitter

Meninges


Cerebrospinal fluid


Blood brain barrier

Definition 5 of 97
Multiple sclerosis has _____ lymphocytes/uL, both normal and reactive.

50 or fewer


100-150

more than 200

negative

Definition 6 of 97
What is the major beta globulin seen in CSF?

Gram Staining

Reactive Lymphocytes

Albumin


Transferrin

,Definition 7 of 97
What is the reagent used in Rose Jones test and what is the result if positive?

Trichloroacetic acid (tca)
sulfosalicylic acid (ssa)

Normal: > 0.77 indicates igg production


Reagent: Ammonium Sulfate
+ result: White Ring

Gram staining

Term 8 of 97
Cryptococcus neoformans

Litmus lysate test uses the blood of _________ termed as "amebocytes" which contains copper
complex which is responsible for its blue color.

- This cell is primarily seen in bacterial meningitis.
- It often contain phagocytized bacteria (associated with bacterial meningitis)

- This bacteria is frequently associated with AIDS.
- Gram stain produces a starburst pattern
- India Ink is used to detect capsule and budding yeast of this bacteria; beware of air
bubbles.

- This checks for the Blood-brain barrier integrity. Checks Whether the BBB is intact or
compromised.

Definition 9 of 97
What is the normsl value of CSF IgG index?

Normal: > 10.77 indicates Igg production

Normal: > 0.23 indicates Igg production

Normal: > 0.77 indicates IgG production


Normal: > 100.77 indicates Igg production

, Definition 10 of 97
What is the gold standard for detection of bacterias in CSF?

Culture and sensitivity

Acid-fast staining

Gram positive


Gram staining

Definition 11 of 97
Lymphoblast are seen in what specific type of Leukemia?

Acute Lymphocytic Leukemia (ALL)

Leukemia, Lymphoma, HIV


Fluorescent Treponemal Antibody-absorption (fta-abs)

Trichloroacetic acid (tca)

Definition 12 of 97
A Qualitative tests is used for the detection of its absence or presence of something. Give the
qualitative tests for for protein in CSF?

Reagent: Ammonium Sulfate
+ result: Cloudy Precipitate

Trichloroacetic acid (TCA)
Sulfosalicylic acid (SSA)

Venereal Disease Research Laboratories (VDRL)


Nonne-Apelt
Rose Jones
Pandy's
Nogochi
Colloidal Gold Test

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