Psychopharmacology Drugs the Brain And Behavior 4th Edition meyer Nursing
k k k k k k k k k
Test Bank
k k
,Psychopharmacology Drugs the Brain And Behavior 4th Edition meyer Nursing k k k k k k k k k
Test Bank
k k
Test Bank k
to accompany
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Psychopharmacology, Forth Edition k k
Meyer k• kQuenzer
Chapter 1: Principles of Pharmacology k k k k
Multiple Choice k
1. k refer(s) to specific molecular changes that occur when a drug binds to a
k k k k k k k k k k k k
kparticular target site or receptor, while
k are the resulting widespread alterations
k k k k k k k k
in function.
k k
a. Drug action; therapeutic effects
k k k
b. Side effects; drug effects
k k k
c. Therapeutic effects; side effects k k k
d. Drug action; drug effectsk k k
Answer: d k
Textbook Reference: Pharmacology: The Science of Drug Action
k k k k k k k
2. After drug administration has occurred, the amount of drug in the blood that is free to
k k k k k k k k k k k k k k k
bind at specific target sites is referred to as
k k k k k k k k k
a. the therapeutic dose.
k k
b. first-pass effects. k
c. bioavailability.
d. ED50.
Answer: c k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
3. The specific molecular changes that occur when a drug binds to a particular target site
k k k k k k k k k k k k k k
or receptor are referred to as
k k k k k k
a. drug effects. k
b. drug action. k
c. side effects. k
d. placebo effects. k
Answer: b k
Textbook Reference: Pharmacology: The Science of Drug Action
k k k k k k k
4. Which of the following is not a possible explanation for placebo effects?
k k k k k k k k k k k
a. Pavlovian conditioning k
b. Genetic variation k
c. Drug competition k
d. Expectation of outcome k k
Answer: c k
Textbook Reference: Pharmacology: The Science of Drug Action
k k k k k k k
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,Psychopharmacology Drugs the Brain And Behavior 4th Edition meyer Nursing k k k k k k k k k
Test Bank
k k
5. The administration of oxytocin has been proposed as a treatment for autism. k k k k k k k k k k
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
6. Which factor does not affect the pharmacokinetics of a drug?
k k k k k k k k k
a. Route of administration
k k
b. Lipid solubility k
c. Depot binding k
d. Drug action k
Answer: d k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
7. First-pass metabolism occurs when drugs are taken
k k k k k k
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
8. The area postrema is one area in the brain where the
k k is not complete.
k k k k k k k k k k
a. cerebrospinal fluid k
b. blood–brain barrier k
c. choroid plexus k
d. phospholipid membrane k
Answer: b k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
9. First-pass metabolism occurs with orally administered drugs because
k k k k k k k
a. their absorption is slowed by food.
k k k k k
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way to
k k k k k k k k k k k k k k k
general circulation.
k k
c. drugs must first survive the acidic environment of the stomach.
k k k k k k k k k
d. salivary enzymes in the mouth begin the process of metabolism.
k k k k k k k k k
Answer: b k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
10. Toxic substances in the blood trigger a vomiting response by activating the
k k k k k k k k k k k
a. blood–brain barrier. k
b. choroid plexus. k
c. area postrema.
k
d. median eminence. k
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Test Bank
k k
Answer: c k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
11. Drugs administered _ have the most rapid onset of action.
k k k k k k k k
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
12. Ionization of a drug depends on the of the solution and the
k k k k k k k k k k of the
k
drug.
k
a. pH; pKa k
b. pKa; pH k
c. concentration; lipid solubility k k
d. pH; concentration
k
Answer: a k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
13. The absorption of a drug depends on all of the following except
k k k k k k k k k k k
a. lipid solubility.
k
b. ionization.
c. body temperature.k
d. the concentration of the drug.
k k k k
Answer: c k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
14. Drugs that are should be avoided by women of childbearing age.
k k k k k k k k k
a. teratogenic
b. able to cross the placental barrier
k k k k k
c. psychoactive
d. highly lipid-soluble k
Answer: a k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
15. Agents that induce developmental abnormalities in a fetus are known as
k k k k k k k k k k
a. psychoactive drugs. k
b. illicit drugs. k
c. teratogens.
d. placental drugs. k
Answer: c k
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
k k k k k k
16. Depot binding is said to occur when drugs
k k k k k k k
a. bind to their target sites.
k k k k
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