Exam (elaborations)
MCB 301 Final Exam Study Guide Q&A’S Latest Update
- Course
- Institution
MCB 301 Final Exam Study Guide Q&A’S Latest Update
[Show more]
Content preview
MCB 301 Final Exam Study Guide Q&A’S LatestUpdate
Mupirocin - ✔✔Binds aminoacyl tRNA synthetase for isoleucine and inhibits activity
Trimethoprim - ✔✔Inhibits dihydrofolate reductase and disrupts tetrahydrofolic acid
synthesis
Why isn't Trimethoprim effective against humans? - ✔✔While humans make
dihydrofolate reductase enzyme target, Trimethoprim binds with lower affinity than the
bacterial enzyme
Peptidoglycan is located where for gram positives - ✔✔Outer layer (thick)
Peptidoglycan is located where for gram negatives - ✔✔Periplasm (between outer
and inner layer membranes)
First/second step of peptidoglycan synthesis - ✔✔In cytoplasm, NAM linked to
peptide
Third step of peptidoglycan synthesis - ✔✔NAM-peptide binds bactoprenol in cell
membrane
Fourth step of peptidoglycan synthesis - ✔✔NAG linked to NAM-peptide
Fifth step of peptidoglycan synthesis - ✔✔NAG-NAM-peptide transported across cell
membrane to outside by bactoprenol
, Sixth step of peptidoglycan synthesis - ✔✔NAG-NAM-peptides linked together to
form long chains (glycan strands or peptidoglycan strands or PG strands)
Seventh step of peptidoglycan synthesis - ✔✔Glycan strands cross-linked together
Penicillin structure - ✔✔Beta-lactam ring
Cross-linking enzymes are also known as - ✔✔Penicillin binding proteins
Why do Penicillin binding proteins bind penicillin - ✔✔PBPs function is to cross-link
the PG strands which involves cleavage of D-ala-D-ala in the peptides. D-ala-D-ala looks
like B-lactam rings; therefore, PBPs bind irreversibly to the antibiotic
Actinomycetes - ✔✔Gram-positive bacteria with high GC content (63-78%) that form
branching filaments (hyphase) and spores (not endospores)
Ex: Actinomyces, Nocardia, Streptomyces
Makes up 50% of the soil Actinomycetes - ✔✔Streptomyces
Streptomyces have over ____ number of species - ✔✔500
Streptomyces - ✔✔50% of soil Actinomycetes
>500 species
Genome: linear chromosome; >8Mbp and 69-73% GC conent
Multinucleate aerial filaments called sporophores
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Examsplug. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79271 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now