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NUR2474 Exam 1 –Drugs: Study Guide Complete With Solutions
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NUR2474 Exam 1 –Drugs: Study Guide Complete With Solutions
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NUR2474 Exam 1 –Drugs: Study Guide Complete WithSolutions
Cholinesterase inhibitors interactions Right Ans - Anticholinergics, first
generation anithistamines, TCA's, conventional antipsychotics
Cholinesterase inhibitors Right Ans - Donepezil
Rivastigmine
Galantamine
neostigmine
Cholinesterase inhibitors side effects Right Ans - dizziness, GI upset,
fatigue, headache
Cholinesterase inhibitors adverse effects Right Ans - bradycardia
bronchoconstriction
Donzepil side effects Right Ans - nausea vomitting diarrhea urinary
urgency bronchoconstriction bradycardia orthostatic hypotension
Rivastigmine Right Ans - side effects likely and more intense. caution with
PUD bradycardia sick sinus syndrome urinary obstruction, lung disease.
transdermal route lowers intensity of side effects.
Neostigmine Right Ans - prevents acetylcholine degradation. myasthenia
gravis, parkinsons dementia, alzheimers
Galantamine Right Ans - caution use in asthma or copd . avoid
anticholinergics 1st gen antihistamines, TCAs, conventional antipsychotics
because they reduce effects.
Nmda blocker Right Ans - antagonist.
Memantime Right Ans - NMDA blocker
Memantime adverse reactions Right Ans - skin reactions. steven johnsons
syndrome. erythema multiforme. bradycardia, hypertensions, angina.
, Memantime side effects Right Ans - dizziness headache confusion diarrhea
or constipation
Immunomodulators Right Ans - interferon beta
Interferon beta Right Ans - FLu like symptoms, hepatotoxicity,
myelosuppression (decreases all blood cells monistor cbc frequently)
injection site reaction. depressions
Interferon beta drug interactions Right Ans - other immunosuppressive
drugs
Immunosuppressants Right Ans - Mitoxantrone
Mitoxantrone Right Ans - decreases autoimmune destruction of myelin.
Mitoxantrone side effects Right Ans - myelosuppression(montior cbc)
increased risk for infections. no live virus immunizations. cardiotoxicity
(irreverisble damage to ejection fraction) fetal harm (growth delay and
prematurity)
Mitoxantrone reversible injuries Right Ans - hair loss, Gi mucosa,
amenorrhea, sysmptoms of allergy, acute myelogenous leukemia.
Seizure meds Right Ans - IV benzos (Diazepam/lorazepam
longterm- phenytoin
What antiseizure meds do Right Ans - either suppress discharge or
neurons or suppress progation of seizure activity from the focus to other
areas of the brain.
5 basic mechanisms of antiseizure drugs Right Ans - suppress sodium
influx
suppress calcium influx
promote potassium efflux
block receptors for glutamate
increase GABA
prototype drugs for seizures Right Ans - phenytoin oxcarbazepine
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