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PMCOL 200 - GI EXAM LATEST UPDATE
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PMCOL 200 - GI EXAM LATESTUPDATE
gastric diseases - Answer peptic ulcers
gastrogesophageal reflux disease
nausea and vomiting
gastrointestinal motility problems
acid peptic disorder - Answer group of disorders involving either excessive acid
secretion or erosion of the mucous lining
includes GERD and peptic ulcers
what is the target of drugs used to help acid peptic diseases - Answer manipulate acid
secretion
promote mucosa defense
get rid of helicobacter pylori
the stomach compartments - Answer antrum and fundus
parietal cells - Answer found in the fundus responsible for secretion of HCl
how is acid secreted from the parietal cells - Answer H/K ATP pump moves acid from
parietal cell to gastric lumen
What is carbonic anhydrase? - Answer RBC enzymes that catalyze the rapid
interconversion of carbon dioxide and water to bicarbonate and H+ ions. This
conversion is normally slow in the plasma but CA causes the conversion to occur
rapidly.
G cells - Answer found in the antrum
secrete gastrin
what does gastrin bind to - Answer CCK receptors on parietal cells
what cells do gastrin stimulate - Answer ECL cells
which release hsitamine from H2 receptors
vagus nerve and the enteric nervous system - Answer post-ganglionic neurons of the
, enteric nervous system release acetylcholine which bind to M3 receptors on parietal
cells
D cells - Answer release somatostain
inhibit gastrin release from G cells
Antacids - Answer weak bases
neutralize stomach acid by reacting with protons in the lumen of the gut
large doses necessary to change the pH of the stomach
two popular antacids - Answer magnesium chlordie
- laxative effects
- increases motility
alluminium hydrozude
- constipation action
- slows motility
nether are absorbed in the gut.
proton pump inhibitors - Answer omeprazole
decrease bioavailabity of B12
omeprazole - Answer lipophillic
weak base
diffuse onto pairetal cells and inactivate the H/K pump which inhibits acid secretion
hypergastrinemia - Answer caused by prolonged use of omeprazole can lead to excess
gastrin in the stomach
- increased risk of cancer
nausea and vomitting - Answer defense againt food poisining
motion sickness
best wa to cure upset stomach - Answer letting the bacteria rid itself from your body
anti emetics - Answer deal with nausea and vomiting caused my motion sicenss
bismuth subsalicylate - Answer Pepto Bismol
hydrlozed into bismuth oxychloride and salicylic acid
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