mothers who are RH- and unimmunized should receive ____________ prior to
procedures as prophylaxis. - ANSWER✔✔300 mg IM Rh Immune Globulin
CVS - Chorionic Villus Sampling - ANSWER✔✔tests tissue from the placenta -
used to obtain trophoblast cells for analysis; transcervical or transabdominal
approach depending on placental location
when is a CVS performed? - ANSWER✔✔10-13 weeks
contraindications for CVS - ANSWER✔✔maternal Rh sensitization, active
vaginal/cervical infection, uterine fibroids, vag bleeding in last 2 weeks, marked
retroverted/retroflexed uterus
,Cordocentesis (PUBS - Percutaneous Umbilical Blood Sampling) procedure -
ANSWER✔✔tests fetal blood - usually sampled from where the cord enters the
placenta; umbilical vein preferred due to less risk of fetal bradycardia
when is PUBS performed? - ANSWER✔✔after 17 weeks
How is blood taken during PUBS confirmed to be fetal? - ANSWER✔✔MCV
>100
What does PUBS stand for? - ANSWER✔✔Percutaneous Umbilical Blood
Sampling - also called cordocentesis
what does PUBS detect? - ANSWER✔✔fetal infections, blood disorders, and
chromosomal abnormalities. does not give information about neural tube defects.
most common complication from PUBS? - ANSWER✔✔bleeding from cord
puncture site
what are signs of pregnancy? - ANSWER✔✔hegar sign, chadwick sign, goodell
sign
hegar sign - ANSWER✔✔lower uterine softening, presents as early as 4 weeks
lasts until week 12
chadwick sign - ANSWER✔✔change of labia, cervical , or vaginal color from
pink to bluish violet - noted as early as 6 weeks
,goodell sign - ANSWER✔✔cervical softening due to increased vascularization,
vessels below the uterus engorge from tissue hypertrophy
when is the first trimester? - ANSWER✔✔time from fertilization to the 12th week
of pregnancy - includes embryonic stage (weeks 3-8)
major occurrences of first trimester - ANSWER✔✔implantation
major organ development
bone and tooth bud development
sexual organs distinguishable
nail beds form
spontaneous fetal movements begin
heartbeat audible via doppler in 12th week
some reflexes may be present (babinski)
when is the second trimester? - ANSWER✔✔13th week to the end of week 26
the second trimester is also called the - ANSWER✔✔"honeymoon" period
major occurrences of the second trimester? - ANSWER✔✔bone formation
urine is excreted into the amniotic fluid
fetal brain/CNS development
fetal lung/alveolar development
fetal startle reflex present
, eyes and ears develop
sucking motions may be present
subcutaneous fat begins to accumulate
what occurs late in second trimester? - ANSWER✔✔swallowing, hair patterns,
lanugo, vernix, surfactant, fingerprints, testes begin to descend, sleep/wake
patterns noticeable
quad screen - ANSWER✔✔measures amount of 4 markers in maternal blood to
help diagnose spina bifida, down syndrome, or trisomy 18
what are the four markers the quad screen tests for? - ANSWER✔✔alpha-
fetoprotein (AFP) - produced by fetus
human chorionic gonadotropin (hCG) - produced by placenta
estriol unconjugated - produced by placenta and fetus
dimeric inhibin-A - produced by placenta and ovaries
when is the quad screen performed? - ANSWER✔✔between weeks 15 - 22
a positive quad screen may be followed up with what to confirm? -
ANSWER✔✔amniocentesis
inhibin-A in a quad screen increased the likelihood of identifying
____________________ and decreases the risk of ______________________. -
ANSWER✔✔down syndrome, false positives
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