, Exam-BIPN 102 Midterm 2; Questions and Answers
Rated A+
how much oxygen is diffusing out of the alveoli
fick's equation Correct Ans-V = ((PA-Pb)*A*D/)T OR V/A = ((PA-Pb)*D/)T
V = flow rate
PA-Pb = pressure gradient
A = surface area
D = diffusion coefficient
T = thickness/distance
V/A = net rate of particles moving through A; flux
(PA-Pb)/T = change in P over a distance
D*A/T = diffusion capacity, D(L)
fibrosis and fick's equation Correct Ans-smoke cannot be destroyed by macrophages -->
production of collagen --> collagen/scar tissue on the alveoli --> increase in T --> decrease in
gas exchange
, Exam-BIPN 102 Midterm 2; Questions and Answers
Rated A+
emphysema and fick's equation Correct Ans-airway obstruction as a result of inorganic
particles --> triggers the production of elastase which breaks down elastin --> alveoli lose
elastance --> alveoli recoil --> increase in T and decrease in A --> lower gas exchange
edema and fick's equation Correct Ans-swelling and increased fluid in the interstitial space
--> increase in T (greater diffusion distance) --> decrease in gas exchange
asthma and fick's equation Correct Ans-hyper responsiveness/sensitivity of the airways -->
airway obstruction, swelling, mucus, etc --> increase in T --> decrease in gas exchange
diffusion limited gas exchange Correct Ans-- gas exchange is limited by the diffusion rate of
gas from the alveoli to the circulatory system
- the pressure in the capillaries and pressure in the alveoli never equilibrate
- net diffusion into pulmonary capillary depends on magnitude of partial pressure gradient
- this occurs with oxygen in abnormal situations
perfusion limited gas exchange Correct Ans-- gas exchange is limited by the blood flow rate
through the capillaries
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