Strasinger Chapter 5 Chemical Examination of Urine Questions and Correct Answers
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Strasinger
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Strasinger
Reagent strips these examine = pH, protein, glucose, ketones, blood, bilirubin, urobilinogen, nitrite, leukocytes, specific gravity
Reagent strip bottles store these at room temperature
QC is done with positive and negative controls every 24 hrs
Confirmatory testing using different methods to de...
Strasinger Chapter 5 Chemical
Examination of Urine Questions and
Correct Answers
Reagent strips ✅these examine = pH, protein, glucose, ketones, blood, bilirubin,
urobilinogen, nitrite, leukocytes, specific gravity
Reagent strip bottles ✅store these at room temperature
QC is done with positive and negative controls every ✅24 hrs
Confirmatory testing ✅using different methods to detect the same substances
pH ✅kidneys and lungs regulate this acid base in the body.
Clinical significance of pH ✅aids in determining disorders of the metabolic or
respiratory origin.
Urinary pH ✅may indicate a disorder resulting from the kidneys inability to secrete or
to reabsorb acid or base.
Urine pH control ✅mainly the diet
pH # ✅fresh urine does not reach above 8.5. This would indicate improper storage or
abnormal conditions. Request new urine sample
Reagent strip reaction ✅methyl red --> bromthymol blue
Protein in urine ✅the most indicative of renal disease
major serum found in normal urine ✅albumin
Tamm-horsfall protein ✅uromodulin
Uromodulin is produced ✅in the distal convoluted tubule
Clinical significance of protein ✅can help diagnose, prerenal, renal, and post renal
Prerenal proteinuria ✅caused by conditions affecting the plasma prior to reaching the
kidneys
, Bence Jones protein ✅possible multiple myeloma
Renal proteinuria ✅renal disease resulting in glomerular or tubular damage
glomerular proteinuria ✅resulting damage lets more proteins pass and eventually
RBC's and WBC's
Proteinuria can be associated with... ✅extreme exercise, and also cause pre-
eclampsia during pregnancy
Micro albuminuria ✅can show in those with diabetes mellitus 1&2
orthostatic proteinuria ✅evident in those that are vertical but disappears when
horizontal. Good for morning urine collection
tubular dysfunction disorders ✅heavy metals, severe viral infections, Fanconi
syndrome
Post renal proteinuria ✅passing of urine through the urinary tracts producing exudates
from the interstitial fluid
reagent strip reaction ✅yellow to blue-green
False-positive reagent strip reading ✅specimens with a high specific gravity,
pigmented urine
Sulfosalicylic Acid test ✅performed under certain conditions, must be centrifuged and
is a cold precipitation test
creatinine reagent strip reaction ✅peroxidase --> chromogen to orange-blue
Glucose ✅most frequently performed test on urine
Diabetes mellitus ✅early diagnoses can be done through urine and blood test.
symptoms are non-specific and this can lead to symptoms going undiagnosed.
Clinical significance ✅reabsorbed into the proximal convoluted tubule in normal
conditions and is by active transport
Renal threshold ✅160-180 mg/dL
Glycosuria ✅usually preceded my a meal of high glucose content
hyperglycemia ✅can occur during pregnancy and is gestational diabetes
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