Hematology - Lecture 3 - RBC
What is hematology? - ANS Morphology of Mammalian Erythrocyte in Peripheral
Blood.
What is the RBC function? - ANS carry Ox
What are the RBCs made up of? - ANS - 60-65% water
- 30-35% Hb ( 95% dry weight)
What is HB? - ANS heme + globin molecule
How many Hb are in 1 RBC? - ANS 4 x 108 Hb molecules
How is Hemoglobin concentration (Hb) reported? - ANS grams of hemoglobin per
deciliter of blood (g/dL)
What is the hemoglobin concentration of whole blood? - ANS - red cells are
approximately 33% hemoglobin,
- normally is about one third of the HCT (PCV)
Erythrocyte Indices are calculated values using ? - ANS PCV, and Hb g/dL
What are the erythrocytes indices? - ANS - MCV
- MCH
- MCHC
What does MCV stand for? - ANS Mean Corpuscular volume (Average size of
RBC fentalitres)
What does MCH stand for? - ANS Mean Corpuscular Hb (How much Hb in RBC)
What does MCHC stand for? - ANS Mean Corpuscular Hb concentration (Hb/
RBC)
What machine calculates the Erythrocytes indices? - ANS Lasercyte
, What are the RBC indices in French? - ANS - VGM
- TGMH
- CGMH
How is MCV calculated? - ANS = PCV(%) x 10 ÷ #RBC = cell size in femtoliters
(10-15 liters) (Know which is numerator and denominator)
Define
Normocytic
Microcytic
Macrocytic - ANS - normal-sized red blood cells, but you have a low number of
them
- small-sized red blood cells, but you have a low number of them
- large-sized red blood cells, but you have a low number of them
What is the RBC size in Microns for;
Dog, pig, cat, horses, cattle, sheep, goat? - ANS 7, 6, 5.8, 5.8, 5.8, 4.5, 3.2
What is MCH? - ANS - Average weight of Hb in an RBC
- Variability between species because of the different sizes of RBCs
How is MCH calculated? - ANS HB (g/dl) / # RBC (x 109/ul ) x 10
- Unit is pg (10 -12 g)
What is MCHC? - ANS Concentration of Hb in whole RBC volume
How is MCHC calculated? - ANS =Hb(g/dL) / PCV x 100
Most mammals fall in the range of 30-36 g/dl
This value is consistent from specie to specie and is around 33
Define
Normochromic
Hypochromic
Hyperchromic - ANS - form of anemia in which the concentration of hemoglobin
in the red blood cells is within the standard range. However, there are insufficient
numbers of red blood cells
- generic term for any type of anemia in which the red blood cells (erythrocytes)
are paler than normal.
- an anemia with increase of hemoglobin in individual red blood cells and
reduction in the number of red blood cells
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