Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a patient who is having a
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computed tomography (CT) scan. The nurse working on the oncology unit adm
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inisters chemotherapy to patients who have cancer. At the Public Health Depart
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ment, a nurse administers a measles-mumps-rubella (MMR) vaccine toa 14-
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month-
old child as a routine immunization. Which branch of pharmacology best descri
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bes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are invol
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ved with clinical pharmacology or pharmacotherapeutics, which is a branch of
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pharmacology that deals with the uses of drugs to treat, prevent, and diagnose d
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isease. The radiology nurse is administering a drug to help diagnose a disease.
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The oncology nurse is administering a drug to help treat adisease. Pharmacoeco
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nomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body andp 7 7 7 7 7 7 7 7 7
harmacokinetics is how the body acts on the body. 7 7 7 7 7 7 7 7
2.
A physician has ordered intramuscular (IM) injections of morphine, a narcot
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ic, every 4 hours as needed for pain in a motor vehicle accident victim.The nurs
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e is aware this drug has a high abuse potential. Under what categorywould mor
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phine be classified? 7 7
A) Schedule I 7
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B) Schedule II
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C) Schedule III 7
D) Schedule IV 7
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs becau
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se of severe dependence liability. Schedule I drugs have high abuse potential a
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nd no accepted medical use. Schedule III drugs have a lesser abuse potential th
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an II and an accepted medical use. Schedule IV drugs havelow abuse potential
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and limited dependence liability.
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3.
When involved in phase III drug evaluation studies, what responsibilitie
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swould the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects 7 7 7 7 7 7 7
D) Conducting research to determine effectiveness of the drug 7 7 7 7 7 7 7
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in whichpa
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tients are asked to record any symptoms they experience while taking thedrug
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s. Nurses may be responsible for helping collect and analyze the information t
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o be shared with the Food and Drug Administration (FDA) butwould not cond
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uct research independently because nurses do not prescribe medications. Use
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of animals in drug testing is done in the preclinical trials. Select patients who
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are involved in phase II studies to participate in studies where the participants
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have the disease the drug is intended to treat. These patients are monitored clo
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sely for drug action and adverse effects. Phase I studies involve healthy huma
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n volunteers who are usually paid for their participation. Nurses may observe
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for adverse effects and toxicity.
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4.
What concept is considered when generic drugs are substituted for bran
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dname drugs?
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A) Bioavailability
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