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BCH 361 Ch. 7 Study Questions with 100% Correct Verified Solutions| Latest Update
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BCH 361 Ch. 7 Study Questions with100% Correct Verified Solutions|
Latest Update
An allosteric enzyme that follows the concerted mechanism (MWC model) has a T/R
ratio of 300 in the absence of substrate. Suppose that a mutation reversed the ratio.
Note that R is the highly active form of the enzyme and T is the less active form of
the enzyme.
Select all of the effects this mutation will have on the relationship btw the rate of
the reaction (V) and substrate concentration ([S]).
A. The plot of V versus [S] would be shaped like an S, sigmoid
B. The plot of V versus [S] would be shaped like a hyperbola
C. The enzyme would be less active
D. The enzyme would likely follow Michaelis-Menten kinetics
E. The enzyme would be mostly in the R form - Answer B, D, E
What are characteristics of allosteric enzymes?
A. They conform to Michaelis-Menten kinetics
B. They interconvert btw a more active form and a less active form
C. They may have binding sites for regulatory molecules that are separate from
active sites
D. They generally have more than one subunit
E. They tend to have a hyperbolic curve of Vo vs. [S]. - Answer B, C, D
Feedback inhibition is important for the regulation of many metabolic pathways.
Which of the statements are examples of feedback inhibition? Select all that apply
A. The production of tryptophan is halted by the presence of excess tryptophan
B. Arsenic binds to pyruvate dehydrogenase and inhibits the enzyme
, C. The beginning of glycolysis is inhibited by high levels of ATP in the cell
D. An intermediate of glycolysis activates an enzymes downstream in the pathway
E. The lac operon is not transcribed when there is no lactose present - Answer A, C
Match the condition w/ the statement that describe it.
This condition will result in the highest rate.
A. [S]= 10Km
B. [S]= Km
C. [S]= 0.1Km - Answer A
Match the condition w/ the statement that describe it.
Doubling [S] will have little effect on the rate.
A. [S]= 10Km
B. [S]= Km
C. [S]= 0.1Km - Answer A
Match the condition w/ the statement that describe it.
About 90% of the active sites are occupies by substrate
A. [S]= 10Km
B. [S]= Km
C. [S]= 0.1Km - Answer A
Match the condition w/ the statement that describe it.
Doubling [S] will almost double the rate
A. [S]= 10Km
B. [S]= Km
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