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Geriatric Symptoms & Frailty

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Geriatric Symptoms & Frailty

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  • September 13, 2024
  • 9
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Geriatric Symptoms & Frailty
  • Geriatric Symptoms & Frailty
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GERIATRIC SYMPTOMS & FRAILTY
QUESTIONS AND ANSWERS

nWhat is key to understanding age-related disease? - Recognizing and understanding frailty (also
recognizing signs of pre-frailty)

Frailty can adversely influence... - Outcomes



-- Can take an unexpectedly long time to recover from an acute illness



-- Reduced physiologic reserve to overcome illness



*Impact of COVID-19 on the older adult population (esp. when in an institutionalized setting) - reduced
immunity to begin w/ (as an older adult)

Adaptive homeostasis - Extent that the body can adapt to the physiologic stresses and maintain
homeostasis; will influence susceptibility to illness/injury

What contributes to the loss of "energetics," homeostasis, and physiologic reserve? - Multi-system
dysregulation

Organ systems have built-in ________________ structures and function - Redundant (e.g., O2, digestive,
and metabolic systems interact and work together to deliver "fuel" to the correct structures at the
correct time)

Built-in redundancy - Decline/dysfunction in one system can lead to an increased contribution of... -
Another system

% of margin of loss for most systems before evidence of failure presents - 70

Redundancy allows most organ systems to function adequately UNTIL... - A 30% MINIMUM functional
threshold is crossed

The "tipping point" - Loss of reserve capacity is an important dimension of frailty

Physiological systems are easily tipped over the threshold of clinical failure when... - An acute problem
occurs (e.g., chronic renal insufficiency --> a bout of diarrhea causes dehydration and acute renal failure)

Factors associated w/ frailty and cognitive impairment: - -- Lifestyle and mental health factors

, -- Cardiovascular risk factors



-- Nutritional deficiencies



-- Hormonal imbalance



-- Social factors



-- Inflammation



-- Poor health and medication use



(Overlap present)

Prevalence of frailty - (Looking at >7000 community-dwelling Medicare enrollees over the age of 65)



--15.3% = frail (w/ 3 out of the 5 attributes based on the physical frailty phenotype)



--45.5% = pre-frail (having 1-2 out of the 5 attributes)

Prevalence of frailty in nursing homes = - ~76 (w/ remainder of individuals considered to be pre-frail)

Key risk factors for frailty: - -- Increased age

-- Female

-- Black/Hispanic

-- Lower level of education

-- Lower socioeconomic status

-- Poor self-rated health

-- Presence of co-morbidities

-- Presence of disease

Increased age as a key risk factor for frailty - -- Only 9% in the 65-69 age bracket

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