NUR 323 Exam 4 Study Guide with Questions and Correct Answers
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Course
NUR 323
Institution
NUR 323
Hemophilia *Bleeding disorder resulting in deficits of coagulation factors
*Typically inherited by sons of mothers who carry the trait
Hemophilia A *Classic hemophilia *Factor VIII deficiency *X-linked recessive disorder *Most common form
Hemophilia B *Christmas disease *Factor IX disorder
Apla...
NUR 323 Exam 4 Study Guide with
Questions and Correct Answers
Hemophilia ✅*Bleeding disorder resulting in deficits of coagulation factors
*Typically inherited by sons of mothers who carry the trait
Hemophilia A ✅*Classic hemophilia
*Factor VIII deficiency
*X-linked recessive disorder
*Most common form
Hemophilia B ✅*Christmas disease
*Factor IX disorder
Aplastic Anemia what is it? ✅Pancytopenia: Where all 3 blood cellular components are
low or absent
Aplastic Anemia ✅*Pancytopenia: Where all 3 blood cellular components are low or
absent
*Complete bone marrow suppression or failure
*Rich, red marrow is replaced with fatty yellow substance
*Congenital (autosomal recessive) is called Fanconi Anemia
*Acquired (bone marrow destruction for different reasons)
Causes of acquired aplastic anemia: ✅*Autoimmune response (ex: self-reactive T
cells)
*Infection
*Chemical exposure
*Pharmacological agents
*Radiation
Sickle cell is triggered by what? ✅Sickle cell is triggered by hypoxia, acidosis,
dehydration, fever, and hypothermia
Treatment for Sickle Cell= ✅Treatment for Sickle Cell= HOP to it! (Hydrate,
Oxygenate, Pain)
Sickle Cell treatment: ✅*Address the triggers:
-Isotonic fluid for dehydration
-Warm compresses
-Prevent infection (ex: through hand washing, antibiotics, and vaccinations)
, -Treat fevers quickly
*Pain management strategies:
-Nonpharmacological interventions
-Nonsteroidal anti-inflammatory medications adjunct
-Opioids when necessary (Sickle cell is VERY painful!)
*Bone marrow transplantation:
-Autologous stem cell therapy with human leukocyte antigen-matched sibling
-Cord blood transplants
*Hydroxyurea:
-Increases the level of fetal Hgb.
-Reduces the amount of crises and promotes splenic function.
-Can cause neutropenia.
*Deferoxamine:
-Used if hemolysis results in high levels of free iron.
-Subcutaneous infusion: chelating agent to bind iron.
-Use with vitamin C.
-Monitor for side effects.
*Transfusions of packed RBCs.
*Psychosocial support:
-Sickle Cell Foundation
CBC evaluates what: ✅A CBC is a panel of tests that evaluates the three types of cells
that circulate in the blood
Hemophilia Treatments: ✅*Monitor clotting times and coagulation studies
*Factor replacement (prophylactic or on demand)
-Dose range for factor replacement varies by injury
-Reconstitute and administer IV
*Desmopressin intranasal
*RICE (Rest, Ice, Compression, Elevate) and physical and occupational therapy to
maintain mobility
*Monitor for signs of internal bleeding (especially-intracranial)
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