drugs and the neuroscience of behavior an introduc
2nd edition drugs and the neuroscience of behavior
drugs and the neuroscience of behavio
Connected book
Book Title:
Author(s):
Edition:
ISBN:
Edition:
More summaries for
Drugs and the Neuroscience of Behavior An Introduction to Psychopharmacology 2nd Edition Prus Test Bank
Drugs and the Neuroscience of Behavior An Introduction to Psychopharmacology 2nd Edition Prus Test Bank
COMPLETE TEST BANK FOR Drugs And The Neuroscience Of Behavior: An Introduction To Psychopharmacology 3rd Edition By Adam Prus Latest Update
All for this textbook (8)
Written for
Drugs and the Neuroscience of Behavior An Introduc
All documents for this subject (8)
Seller
Follow
kushboopatel6867
Reviews received
Content preview
Drugs and the Neuroscience of Behavior An
Introduction to Psychopharmacology 2nd Edition Prus
Test Bank
Up until hypnotic sedatives, how did all of the drugs affect dopamine? - ANSWER: by
altering the GABA pathways -- NOT by acting on the GABA receptors themselves
sedative-hypnotics: sedative - ANSWER: low dose produce calming effect at and
general decrease in activity
sedative-hypnotics: hypnotic - ANSWER: higher dose produce drowsiness that can be
sleep-inducing
the brain's downer - ANSWER: GABA
GABA: inhibitory - ANSWER: the neurotransmitter GABA generally reduces molecular
and behavioral activity
GABA-B receptor - ANSWER: a GPCR that causes indirect effects, modulates K+
channel
affects depolarization
GABA-A receptor - ANSWER: a chloride channel causes direct hyperpolarization
basically impossible to drive depolarization after this is hyperpolarized
GABA-A subunits - ANSWER: there are a lot of different combination of alpha (n=6),
beta (n=3), gamma (n=3) subunits
the sedative-hypnotic receptor
2 main types of GABA receptors: - ANSWER: A and B
GABA receptors are - ANSWER: pentamers
5 subunits
each one is a different gene
6 alpha, 3 beta, 5 gamma
lots of different combinations possible which affect affinity for GABA and different
drugs of abuse
GABA-A site - ANSWER: binding GABA (agonist) activates that channel to pass
chloride ions
anesthetic site - ANSWER: propofol, alcohol, quaaludes, neurosteroids
barbiturate site - ANSWER: barbiturates
, benzodiazapine - ANSWER: benzodiazapines
different sites on GABA-A - ANSWER: 3 different sites
all drugs dont compete with GABA, have different sites
all positive allosteric modulators
anxiolytic - ANSWER: relief from anxiety
disinhibition - ANSWER: cognitive and motor impairment ("life of the party")
sedation - ANSWER: decrease in activity
hypnosis - ANSWER: sleep induction
coma - ANSWER: loss of consciousness
death - ANSWER: legal dose (LD50)
pharmacodynamics of barbiturates - ANSWER: GABA-A positive allosteric modulator
(PAM)
pharmacokinetics of barbiturates - ANSWER: developed drugs that last from minutes
to days
therapeutics of barbituates - ANSWER: widely used for treating anxiety, insomnia,
and epilepsy
1930s and 1940s: barbituates - ANSWER: alcohol with drug-like 1st order kinetics
barbiturates therapeutic window - ANSWER: very small
side effects of barbiturates - ANSWER: difficult to separate therapeutic dose from
drowsiness and effects on cognitive and motor function
tolerance of barbiturates - ANSWER: induces changes in liver function requiring
increasing doses
overdose of barbiturates - ANSWER: cause of numerous unintentional and
intentional deaths
the current standard of care - ANSWER: benzodiazapines
pharmacodynamics of benzodiazapines - ANSWER: GABA-A positive allosteric
modulator (PAM)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller kushboopatel6867. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $17.99. You're not tied to anything after your purchase.
