CMB2004 Questions and Answer | Latest Update 2024/2025
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Course
CMB2001
Institution
CMB2001
What is a pathogen?
~~> A microorganism that causes disease e.g. bacteria, fungi, virus,
parasite
For an effective immune response the immune system must...
~~> - be able to recognise and respond to any invading organism
- not over react to benign or self
- be able to direct differ...
✓ ~~> major histocompatibility complex molecules, also called HLA
(human leukocyte antigens)
a collection of cell surface markers that identify the cells as self
Rearrangement of Ig genes
✓ ~~> - Genes rearrange during B cell development to form a functional
gene
- Production of functional immunoglobulin genes involves recombination to
bring gene segments together
- After DNA breaks, a single V and a single J gene segment are joined
together to encode the V region of the light chain
- Similarly, a single V, D and J gene segment are joined together in a single B
cell to encode the V region
Types of segments in heavy and light chains
✓ ~~> V - variable
D - diversity
J - joining
C - constant
Master01 | September, 2024/2025 | Latest update
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