FGCU Pharmacology Exam 1 with
complete solutions 2024/2025
Medication Administration: Nursing Responsibility - ANSWER- Administering the
drug
Assessing drug effects
Intervening to make the drug regimen more tolerable
Providing patient education about drugs and the drug regimen Monitoring the
overall patient care plan to prevent medication errors
Drug Evaluation: Preclinical Trials - ANSWER- Drugs are tested on laboratory
ANIMALS to see if the drug has effects on living tissue organisms and to assess
for adverse effects
Drug Evaluation: Phase I Studies - ANSWER- Chemicals tested on HEALTHY
HUMANS volunteers
Informed consent is obtained
Usually male 150lbs
Women of childbearing age are eliminated
Drug may cause unknown harm to ova
Drug Evaluation: Phase II Studies - ANSWER- Drug trailed on informed PATIENTS
WITH THE DISEASE that the drug is intended to treat
Drug Evaluation: Phase III Studies - ANSWER- Drug used in VAST CLINICAL
MARKET
Drug Evaluation: FDA Approval - ANSWER- Drugs that finish phase III trials are
evaluated by the FDA; if approved my be marketed
Drug Evaluation: Phase IV Studies - ANSWER- Continual evaluation of drug
,The DEA has how many schedules of controlled substances? - ANSWER- 5
DEA Schedule I (3 examples) - ANSWER- High abuse potential and NO accepted
medical use
Heroin, marijuana, LSD
DEA Schedule II (3 examples) - ANSWER- High abuse potential with severe
dependence liability
Narcotics, amphetamines, barbiturates
DEA Schedule III (3 examples) - ANSWER- Less abuse potential than schedule II
and moderate dependence liability
Nonbarbiturate sedatives, nonamphetamine stimulates, limited amounts of
certain narcotics
DEA Schedule IV (3 examples) - ANSWER- Less abuse than schedule III and
limited dependence liability
Some sedatives, anti-anxiety agents, nonarcotic analgesics
DEA Schedule V (3 examples) - ANSWER- Limited abuse potential
Small amounts of narcotics (codeine), antitussives, antidiarrheals
Limited quantities may be purchased directly from a pharmacist
Must be 18 w/ suitable identification
All transactions must be recorded
Generic Drugs - ANSWER- Chemicals that are produced by companies involved
solely in the manufacturing of drugs
Bioavailability of the drug may be different than brand name drug
Less expensive than brand name drug
Why would DAW be written on a prescription? Who writes it? - ANSWER- So that
generic drugs will not be substituted for brand name drugs
It is written by the prescriber.
What are some problems with over-the-counter (OTC) drugs? - ANSWER- Mask
the signs and symptoms of underlying disease, making difficult diagnosis
Could result in drug interactions and interfere with drug therapy
Can result in serious overdoes if not taken correctly
, What is an example of a serious overdoses caused by an OTC? - ANSWER-
Acetaminophen (Tylenol) overdoes can result in liver failure and the need for a
liver transplant
What is pharmacodynamics? - ANSWER- How the drug affects the body (the
mechanism of action)
The study of the interactions between the chemical components of living systems
and foreign in chemicals, including drugs that enter living organisms
What is pharmacokinetics? - ANSWER- The way the body deals with the drug
The study of absorption, distribution, metabolism (biotransformation), and
excretion of drugs
What is the onset of the drug, and is it part of the pharmacodynamics or
pharmacokinetics? - ANSWER- (Pharmacokinetics) how long it will take to see the
beginning of the drugs therapeutic effect
What is a drug half life, and is it part of the pharmacodynamics or
pharmacokinetics? What is the half life affected by? - ANSWER-
(Pharmacokinetics) The drug half life is how long it take the drug to decrease by
half.
Example 100mg acetaminophen given at 1500 half life is p4h
At 1900 the drug will be down to 50mg
At 2300 the drug will be down to 25mg
It is affected by absorption, distribution, metabolism, and excretion.
What is the peak effect, and is it part of the pharmacodynamics or
pharmacokinetics? - ANSWER- (Pharmacokinetics) how long it will take to see the
maximum effect of the drug
What is the duration, and is it part of the pharmacodynamics or
pharmacokinetics? - ANSWER- (Pharmacokinetics) how long the patient will
experience the drug effects
What are agonists, and give an example? - ANSWER- Drugs that interact directly
with receptor sites and cause the same activity that the natural chemicals would
cause at that site
Insulin causes movement of glucose into the cell
What is a competitive antagonist, and give an example? - ANSWER- Drugs that
react with receptor sites to block normal stimulation, producing NO EFFECT
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