TEST BANK FOR Understanding Pharmacology, Essentials for Medication Safety, 2nd Edition,Workman & LaCharity Chapter 9-34 Final Exam
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Course
UNDERSTANDING PHARMACOLOGY
Institution
UNDERSTANDING PHARMACOLOGY
TEST BANK FOR Understanding Pharmacology, Essentials for Medication Safety, 2nd Edition,Workman & LaCharity Chapter 9-34 Final Exam
Drugs that inhibit skeletal muscle contraction by blocking conduction within the spinal cord are known as _____.
A. spasmolytics
(B. peripheral skeletal musc...
TEST BANK FOR Understanding Pharmacology,
Essentials for Medication Safety, 2nd Edition,Workman &
LaCharity Chapter 9-34 Final Exam
Drugs that inhibit skeletal muscle contraction by blocking conduction within the spinal cord are known as
_____.
A. spasmolytics
(B. peripheral skeletal muscle relaxants
C. cholinergic drugs
D. parasympathomimetics ) - CORRECT ANSWER-A. spasmolytics
The binding of the neurotransmitter acetylcholine to the nicotinic-muscle receptors at the
neuromuscular junction enables:
(A. potassium ions to move into the cells.
B. sodium ions to move out of the cells. )
C. sodium ions to move into the cells.
(D. magnesium ions to enter the cells. ) - CORRECT ANSWER-C. sodium ions to move into the cells.
Which of the following types of drugs inhibits muscle contraction at the neuromuscular junction or
within the contractile process?
A. Spasmolytics
B. Peripheral skeletal muscle relaxants
C. Parasympathomimetic drugs
D. Cholinergic drugs - CORRECT ANSWER-B. Peripheral skeletal muscle relaxants
Identify a difference between nondepolarizing blockers and depolarizing blockers.
, B. The nondepolarizing blockers inhibit cholinergic activity by occupying the nicotinic-muscle sites so
that acetylcholine (ACH) cannot bind with the receptors, whereas depolarizing blockers inhibit
cholinergic activity by altering the Nm receptors so that they cannot respond to ACH stimulation. -
CORRECT ANSWER-B. The nondepolarizing blockers inhibit cholinergic activity by occupying the nicotinic-
muscle sites so that acetylcholine (ACH) cannot bind with the receptors, whereas depolarizing blockers
inhibit cholinergic activity by altering the Nm receptors so that they cannot respond to ACH stimulation.
_____ is the only available depolarizing neuromuscular blocking drug.
(A. Pancuronium
B. Atracurium)
C. Succinylcholine
(D. Carbachol) - CORRECT ANSWER-C. Succinylcholine
Which of the following statements is true of nondepolarizing blockers?
A. The nondepolarizing blockers combine with, but do not stimulate, the nicotinic-muscle (Nm)
receptors.
( B. The nondepolarizing blockers allow acetylcholine to combine with the Nm receptors to induce
depolarization.
You Answered
C. The only available nondepolarizing neuromuscular blocking drug available today is succinylcholine.
D. After binding to the Nm receptors, nondepolarizing drugs alter the receptors so that they cannot
respond to endogenous ACH stimulation.) - CORRECT ANSWER-A. The nondepolarizing blockers combine
with, but do not stimulate, the nicotinic-muscle (Nm) receptors.
One of the ways to prolong the effects of a rapidly metabolized skeletal muscle relaxant is to administer
the medication:
A. through an intravenous injection.
B. by intravenous infusion.
C. through an intramuscular injection.
,D. intradermally - CORRECT ANSWER-B. by intravenous infusion.
Neuromuscular blockers inhibit skeletal muscle contraction by interfering with the _____.
A. nicotinic-muscle receptors
B. nicotinic-neural receptors
C. muscarinic receptors
D. ganglionic receptors - CORRECT ANSWER-A. nicotinic-muscle receptors
The drug dantrolene relaxes skeletal muscle by inhibiting the release of which ions from the sarcoplasmic
reticulum?
A. Sodium ions
B. Chloride ions
C. Potassium ions
D. Calcium ions - CORRECT ANSWER-D. Calcium ions
Which of the following types of skeletal muscle relaxants can be considered a cholinergic receptor
antagonist?
A. A nondepolarizing drug
( B. A depolarizing drug
C. A direct-acting cholinergic drug
D. An indirect-acting cholinergic drug ) - CORRECT ANSWER-A. A nondepolarizing drug
Which of the following should be taken into consideration when selecting a neuromuscular blocking drug
for surgical relaxation?
A. Duration of action
B. Time of onset
C. Reversibility of the drug
, D. All of these - CORRECT ANSWER-D. All of these
Austin has accidently taken an overdose of atracurium, a drug belonging to the class of nondepolarizing
blockers. He slips into a state of respiratory paralysis and struggles to control his breathing. On arriving at
the hospital, the doctors give Austin a dose of a certain drug in an attempt to reverse his condition.
Based on the information provided in this scenario, which of the following drugs have the doctors given
Austin?
A. Atropine
B. Oxybutynin
C. Neostigmine
D. Scopolamine - CORRECT ANSWER-C. Neostigmine
The major toxicity associated with neuromuscular blocker overdose is:
A. respiratory muscle paralysis.
B. cardiovascular collapse.
C. hypercalcemia
D. hyponatremia - CORRECT ANSWER-A. respiratory muscle paralysis.
Ella has been taking large doses of a particular neuromuscular blocker over a very long period of time.
Consequently, she has developed signs of respiratory paralysis and has severe trouble breathing. After
Dr. Kurt examines her, he concludes that Ella�s deteriorating health is the result of the growing
concentration of the neuromuscular blocker drug in her system. He prescribes the drug neostigmine to
relieve her symptoms. How will the drug neostigmine help counteract the effects of the neuromuscular
blocker drug?
A. It will inhibit the enzyme acetylcholinesterase so that acetylcholine (ACH) accumulates within the
synaptic junctions.
(B. It will attach itself to the synaptic vesicles containing ACH and prevent ACH from being released into
the synaptic cleft.
C. It will damage the nicotinic-muscle receptors, thereby altering the ability of these receptors to
become stimulated.
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