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MN553 Unit 9 with complete verified solutions.
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MN553 Unit 9 with complete verified solutions.
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MN553 Unit 9 with completeverified solutions
True or False
The FDA regulates OTC medications - answer True
Steps for generics to change to OTC - answer Requires additional
testing
Adds time before generic medication is allowed
Creates an opportunity to profit as a brand OTC
Requirements for OTC medications - answer Low potential for abuse
Treat a condition that the patient can self diagnose
Have to be labeled for appropriate use
Food may affect - answer Drug absorption
Drug metabolism
Drug excretion
True or false
,Drugs have no affect on nutritional status - answer False
How does food accept drug absorption - answer Absorption can be
decreased, delayed, accelerated, or increased by food
What happens if there is food in the GI tract at the time of drug
administration - answer Affects absorption and bioavailability
True or false
Food changes gastric pH - answer True
Example of food binding with medication and decreasing absorption
- answer Tetracycline and milk
True or false
Some drugs are better absorbed with food - answer True
The rate of drug metabolism is affected by - answer Nutrient intake
What kind of diet may increase drug metabolizing enzymes - answer
Low carb, high protein
What type of food may increase the activity of drug metabolizing
enzymes - answer Antioxidant cruciferous vegetables
What foods are associated with CYP3A4 - answer Grapefruit
,Seville orange
Pomelo juice
Grapefruit juice affet on CYP3A4 - answer Contains components that
inhibit CYP3A4
Medications affected by ingestion of grapefruit and how it affects
them - answer Increased levels of:
CCB
Immunosuppressants
Erythromyacin
Triazolam
Midazolam
Statins
True or false
Grapefruit juice has no affect on oxycodone - answer False
What foods affect CYP1A2 - answer Vegetables (cruciferous)
Methlxanthine containing beverages -caffeine
, Charcoal broiling
How do Vegetables (cruciferous), Methlxanthine containing
beverages, and Charcoal broiling affect drug metabolism - answer
May lead to therapeutic failure
True or false
Some foods can change urinary pH affecting drug excretion - answer
True
What foods alkalinize urine - answer Milk
Vegetabes
Citrus fruits
What foods acidify urine - answer Meat
Fish
Cheese
Eggs
Drug food incompatibilities:
Warfarin - answer Vitamin K containing foods
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