acid peptic disorder - answer✔group of disorders involving either excessive acid secretion or
erosion of the mucous lining
includes GERD and peptic ulcers
what is the target of drugs used to help acid peptic diseases - answer✔manipulate acid secretion
promote mucosa defense
get rid of helicobacter pylori
the stomach compartments - answer✔antrum and fundus
parietal cells - answer✔found in the fundus responsible for secretion of HCl
how is acid secreted from the parietal cells - answer✔H/K ATP pump moves acid from parietal
cell to gastric lumen
What is carbonic anhydrase? - answer✔RBC enzymes that catalyze the rapid interconversion of
carbon dioxide and water to bicarbonate and H+ ions. This conversion is normally slow in the
plasma but CA causes the conversion to occur rapidly.
G cells - answer✔found in the antrum
secrete gastrin
what does gastrin bind to - answer✔CCK receptors on parietal cells
what cells do gastrin stimulate - answer✔ECL cells
which release hsitamine from H2 receptors
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