NUR 3145 EXAM 1 QUESTIONS WITH COMPLETE
SOLUTIONS
Difference between USP and FDA. Correct Answers U.S
Pharmacopenia: develop manufacturing std. (purity, strength,
labeling, package); FDA: enforce std. set by USP - both work
together w US Congress and Supreme Court to protect public
Drug-Drug interactions: what are some consequences? Correct
Answers Intensification of effects: increased therapeutic effects
and increased adverse effects; reduction of effects: reduced
therapeutic effects and reduced adverse effects; creation of a
unique response
Drug-receptor interactions: agonist vs. antagonists (ex.beta)
Correct Answers Agonist: turns on response (beta: affects heart,
beta 1 increases HR, mimics the response the heart would do on
its own)
Antagonists: blocks the response, turns off (alpha/beta blocker)
Drug-receptor interactions: partial agonists vs. nonreceptor
responses Correct Answers Partial agonists: do the job but not
quite as much as an agonist; the drug has multiple affects
Nonreceptor responses: drugs that don't effect receptors at all
(ex. antibiotics)
How does one prevent an adverse reaction? Correct Answers
Preadministration data, proper dosage and administration,
consider pharmacokinetic and dynamic properties, does food
affect the drug?
, Interpatient variability in drug response (measurement) Correct
Answers The ED50 vs. LD50: effective/lethal dose for 50% of
the population at that does. It is ideal to have a big difference
between the ED and LD
Interpatient variability: therapeutic index Correct Answers
Ratio of the LD50 to its ED50: can be an overlap between the
curve for the what is effective and what is lethal
Nursing Process: Drug Therapy Analysis and Diagnosis Correct
Answers Judge appropriateness of prescribed regimen; ID
potential health problems the drug can cause; determine patient's
capacity for self-care
Nursing Process: Drug Therapy Assessment Correct Answers
Collect baseline data (history, lifestyle, age, preexisting
conditions, current drugs); ID high risk patients (pregnant,
children, elderly, immunosuppressed); assessment of patient's
capacity for self care
Nursing Process: Drug Therapy Evaluation Correct Answers
Therapeutic responses, adverse drug reactions and interactions,
adherence to the prescribed regimen, satisfaction with treatment
Nursing Process: Drug Therapy Implementation Correct
Answers Drug administration, patient education, interventions
to promote therapeutic effects, interventions to minimize
adverse effects
SOLUTIONS
Difference between USP and FDA. Correct Answers U.S
Pharmacopenia: develop manufacturing std. (purity, strength,
labeling, package); FDA: enforce std. set by USP - both work
together w US Congress and Supreme Court to protect public
Drug-Drug interactions: what are some consequences? Correct
Answers Intensification of effects: increased therapeutic effects
and increased adverse effects; reduction of effects: reduced
therapeutic effects and reduced adverse effects; creation of a
unique response
Drug-receptor interactions: agonist vs. antagonists (ex.beta)
Correct Answers Agonist: turns on response (beta: affects heart,
beta 1 increases HR, mimics the response the heart would do on
its own)
Antagonists: blocks the response, turns off (alpha/beta blocker)
Drug-receptor interactions: partial agonists vs. nonreceptor
responses Correct Answers Partial agonists: do the job but not
quite as much as an agonist; the drug has multiple affects
Nonreceptor responses: drugs that don't effect receptors at all
(ex. antibiotics)
How does one prevent an adverse reaction? Correct Answers
Preadministration data, proper dosage and administration,
consider pharmacokinetic and dynamic properties, does food
affect the drug?
, Interpatient variability in drug response (measurement) Correct
Answers The ED50 vs. LD50: effective/lethal dose for 50% of
the population at that does. It is ideal to have a big difference
between the ED and LD
Interpatient variability: therapeutic index Correct Answers
Ratio of the LD50 to its ED50: can be an overlap between the
curve for the what is effective and what is lethal
Nursing Process: Drug Therapy Analysis and Diagnosis Correct
Answers Judge appropriateness of prescribed regimen; ID
potential health problems the drug can cause; determine patient's
capacity for self-care
Nursing Process: Drug Therapy Assessment Correct Answers
Collect baseline data (history, lifestyle, age, preexisting
conditions, current drugs); ID high risk patients (pregnant,
children, elderly, immunosuppressed); assessment of patient's
capacity for self care
Nursing Process: Drug Therapy Evaluation Correct Answers
Therapeutic responses, adverse drug reactions and interactions,
adherence to the prescribed regimen, satisfaction with treatment
Nursing Process: Drug Therapy Implementation Correct
Answers Drug administration, patient education, interventions
to promote therapeutic effects, interventions to minimize
adverse effects
