NUR 3145 Pharmacology Exam 3 Questions With Complete
Solutions
Adrenergic Drug Interactions Correct Answers Alpha and beta
adrenergic and adrenergic antagonists (antihypertensive drugs)
will decrease effectiveness.
Adrenergics and anesthetic drugs increase risk of cardiac
dysrhythmias
Adrenergics given with tricyclic antidepressants and MAO
inhibitors may cause a hypertensive crisis
Adrenergic Medications
Adverse Effects Correct Answers Alpha - adrenergic -
headache, restlessness, excitement, insomnia, euphoria, chest
pain,vasoconstriction, hypertension, tachycardia, palpitations or
dysrythmias
Beta- adrenergic - mild tremors, headache, nervousness,
dizziness; increased heart rate, palpitations, and fluctuations in
blood pressure
Adrenergic Medications
mimic effects of the SNS neurotransmitters Correct Answers
Bronchodilators - albuterol, ephedrine, levalbuterol, salmeterol,
terbulatine
Nasal decongestants - ephedrine, phenylephrine,
tetrahydrozoline
Ophthalmic vasoconstrict or decrease pressure, dilate pupils -
epinephrine
Cardiovascular - vasopressors drugs; vasoconstrictive drugs;
,dobutamine (Dobutrex) IV only, dopamine (Intropin) IV only,
norepinephrine (Levophed) IV only
Adrenergic receptor sites; adrenergic drugs bind and produce
effects. Correct Answers Beta 1 - heart
Beta 2 - bronchial, GI, Uterus
Alpha 1 - postsnaptic effector cells on target organ
Alpha 2 - presnaptic nerve terminals; both control release of
neurotransmitters
Alcohol withdrawal Correct Answers Chlordiazepoxide
(Librium), diazepam (Valium) longest acting , lorazepam
(Ativan) intermediate acting, oxazepam (Serax)
alpha receptors Correct Answers Located in peripheral blood
vessels and smooth muscle
If stimulated
Cause vasoconstriction
If blocked
Cause vasodilation
anti cholinergic drugs inhibits Correct Answers acetylcholine
Dilate pupils (mydriasis)
Decreases secretions
Eyes, mouth, nose
Airway
Slows the GI tract
Speeds up the heart
anti cholinergic drugs used to trat patients with: Correct
Answers GI tract spasms
, Bradycardia and heart block
Parkinson's
Extrapyramidal symptoms or EPS (pseudo-Parkinson's)
Urinary tract spasms
Inadequate bladder capacity
anti depressant meds Correct Answers Tricyclic
antidepressants - potentiate effect of serotonin and
norepinephrine in the CNS
Monoamine oxidase inhibitors (MAOIs) - inhibits monamine
oxidase; thus ↑dopamine, epi, and norepi
Second-generation antidepressants
Selective serotonin reuptake inhibitors (SSRIs)
Serotonin-norepinephrine reuptake inhibitors (SNRIs)
Anti-psychotics Correct Answers Indicted for serious mental
illness: schizophrenia, autism, extreme mania, bipolar;
depression
Mechanism of Action: block dopamine receptors in the brain;
producing a tranquilizing effect
Adverse effects: hemolytic anemia; agranulocytosis; neuroleptic
malignant syndrome (high fever, unstable B/P, myglobinemia),
extrapyramidal sym, pseudoparkinsonism, tardive dyskinesia
(contractions of oral and facial muscles), postural hypotension;
Table 16-9; page 268.
Anti-psychotics 1st generation Correct Answers -conventional
