BCHM 270 Diseases Test with
Questions Solved 100% Correct
|Verified Solutions
Ketoacidosis - Answer Biochemistry:Occurs in uncontrolled Type I diabetes
mellitus. In the absence of insulin, fats are released and cannot absorb glucose.
The liver overproduces ketone bodies as a result. These ketone bodies are acidic,
which results in severe metabolic acidosis.
Symptoms: Blood levels of ketone bodies increase. High acetone levels lead to
fruity odor on the breath. Excretion of glucose and ketone bodies in the urine
results in dehydration fo the body. Acidic ketone bodies lower blood pH, which
results in coma and death if untreated.
Hypercholesteremia - Answer Biochemistry: Body cholesterol increases
Treatment: Statins
Artherosclerosis - Answer Biochemistry: Oxidized LDL leads to development
of macrophage from fatty cells and fatty plaques
Cholelithiasis / Gallstone Disease - Answer Biochemistry: Cholesterol
forms gallstones due to insufficient bile salts
Treatment: Surgical removal of the gall bladder or chenodeoxycholic
acid supplements used to dissolve gallstones
, Familial Hypercholesterolemia
Type II Hyperlipidemia - Answer Biochemistry: Lack of LDL receptor
or overproduction of cholesterol leads to cardiovascular disease
Lipoprotein Lipase Deficiency
Type I Hyperlipidemia - Answer Biochemistry: Genetic mutations. which
prevent the synthesis of lipoprotein lipase, preventing the breakdown of TAGs
in chylomicrons.
Hypertriacylglycerolemia - Answer Biochemistry: Lipoprotein lipase of Apo C-
II deficiency prevents breakdown of TAG
Acute Pancreatitis - Answer Biochemistry: Obstruction o the pancreatic ducts,
blocking secretions. The zymogens are converted into their active forms and
attack the tissue
Cystinuria - Answer Biochemistry: Defective transporter for basic amino
acids including arginine, cystine, ornithine and lysine. These amino acids
cannot be reabsorbed in the kidney and are excreted in the urnie
Hyperammonemia - Answer Biochemistry: Genetic defects of the urea cycle
(carbamoyl phosphate synthase I) or diseases of the liver. Cause the capacity of
the hepatic urea cycle to be far less than normal rates of ammonia generation.
Maple Syrup Urine Disease (MSUD) - Answer Biochemistry: Deficiency of
branched-chain a-keto acid dehydrogenase, which causes elevated levels of
branched-chain ammino acids (isoleucine, valine and leucine) and their a-
keto acids in the blood and urine
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller KenAli. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.99. You're not tied to anything after your purchase.