BCHM 270 Test with Questions
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Solutions
What is correct about the classification of amino acids?
a. Tyr, Phe, Trp, and Ile are glucogenic and ketogenic. b. His, Met, Thr, and Val are
nonessential glucogenic.
c. Leu, Lys, Tyr, Pro, and Ser are nonessential glucogenic.
d. A and B are true.
e. A and C are true. - Answer
Which is true about PKU?
a. Pyridoxine (B6) responsive patients have a better clinical outcome.
b. The most common cause is a defect in cystationine B-synthase.
c. Tyrosine is not hydroxylated, so untreated patients have darker pigmentation.
d. Phenyllacetate and phenylacetate are elevated in the blood.
e. Mental retardation is caused by development of amyloid plaques. - Answer
Which of the following is NOT a pancreatic protease?
a. Carboxypeptidases A and B
b. Trypsin
,c. Elastase
d. Chymotrypsin
e. Pepsin - Answer
Which of the following factors affect the velocity of an enzyme catalyzed reaction?
a. Temperature.
b. Concentration of Substrate.
c. pH.
d. All of the above.
e. None of the above. - Answer d
Amino acids share a common core structure that is comprised of:
a Acarboxyl group (COOH).
b. An alpha-carbon (Ca).
c. An amino group (NHs*).
d. All of the above.
e. None of the above. - Answer d
Which of the following is NOT an interaction responsible for stabilizing the -3
dimensional fold of a protein?
a. Hydrogen bond
b. Hydrophobic interactions
c. Ionic bond
d. Disulfide bond
e. None of the above. - Answer a
The Michaelis constant (Km):
,a. Is the concentration of enzyme required to reach Vmax
b. Is the concentration of substrate required to reach
Vmax/2 c. Is unrelated to the affinity of an enzyme for a
substrate. d. All of the above.
e. None of the above. - Answer b
ATP is the currency of energy in the cell, storing and transferring energy. The energy in
ATP is released by:
a. Pumping protons across the mitochondrial membrane.
b. Hydrolysis of phosphates from the ATP molecule.
c. Coupling of reactions to ATP formation.
d. All of the above.
e. None of the above. - Answer b
The enzymes that catalyze the reactions of the Tricarboxylic acid (TCA) cycle:
a. Are found in the mitochondrial matrix.
b. Require energy in the form of ATP.
c. Are found in the cytosol.
d. Do not recycle the intermediates of the pathways.
e. Regenerate acetyl CoA after completion of the cycle. - Answer a
Aerobic glycolysis describes the conversion of glucose to:
a. Acetvl CoA.
b. Lactate.
c. Phosphoenolpyruvate.
d. Pyruvate.
, e. Glucose. - Answer d
Oxidative Deamination of Amino Acids
а. Occurs primarily in the liver and kidney
b. Glutamate dehydrogenase converts glutamate to a-ketoglutarate and ammonia
c. Glutamate dehydrogenase use NADPH to produce glutamate from a-
ketoglutarate and ammonia.
d. AandC.
e. All of the above. - Answer
Which of the following can lead to steatorrhea?
a. Cystic fibrosis
b. A diet high in carbohydrates
c. Lack of trypsin and chymotrypsin.
d. A and C.
e. All of the above. - Answer d
Which is FALSE for Aminotransferases?
.a High circulating levels of ALT may indicate kidney dysfunction.
b. ALT catalyzes the transfer of alanine to a-ketoglutarate.
c. ASP converts oxaloacetate and glutamate to aspartate and a-ketoglutarate.
d. AST and ALT are elevated in all liver diseases.
e. All are true. - Answer
How does muscle handle ammonia differently than other tissues?
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