Purdue University Global Pharmacology
Midterm Exam| Questions Answered
100% Correct| Rated A
Pharmaceutical phase - ANSWER disintegration of dosage form; dissolution of drug in body
Oral route with rapid drug action - ANSWER Sublingual and Buccal
-low doses must be given
Enteric-coated tablets - ANSWER What dosage form is designed to dissolve in the intestines
rather than the stomach?
protein binding drugs - ANSWER allows part of the drug to be stored and part released as
needed. Drugs that are highly bound to plasma proteins or stored extensively in other tissues
have a long duration of action. Protein binding does not increase the speed of action or
increase metabolism. Protein binding does decrease the speed of action by storing the drug
to be released when needed.
Rectal medication administration - ANSWER sim's position
heavily pad
do not use restroom before the 15 min mark
, Bioavailability - ANSWER A measure of the extent of drug absorption for a given drug and
route (from 0% to 100%). also:
How much drug is available for the body to use
Sublingual nitroglycerin - ANSWER first-line for rapid relief of stable angina.
Systemic vasodilation leads to decrease in Left ventricular EDV (decreased preload), thus
decreased myocardial oxygen demand and relief of angina symptoms
Transdermal Nitroglycerin administration - ANSWER apply patch in the morning; leave on for
minimum of 12hr; apply close to chest area; if patch becomes loose or falls off put another
one on a different site; apply a new patch daily
Child safe medication - ANSWER -Immature organs (kidney and liver)
Cognitive issues must be addressed scubas the ability to understand:
1)the reason for the medication
2)the need for the medication despite the unpleasant taste
3)the need to complete all doses and courses of medication
Primary concern in administering meds to infants:
-maintaining safety with the minimum restraint necessary, administering the correct dosage,
and providing care with as much as comforting as possible
Toddler:
-simple explanations, firm approach, and enlisting the imagination through play may
enhance success with med admin
Preschooler:
-fairly cooperative and respond well to age-appropriate explanations
-some level of choice should be allowed
school-age children:
-may fear bodily injury; permit even more control, involvement in process, and information
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