100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
MICR 270 Study Questions to Guaranteed 100% Pass $14.49   Add to cart

Exam (elaborations)

MICR 270 Study Questions to Guaranteed 100% Pass

 4 views  0 purchase
  • Course
  • MICR 270
  • Institution
  • MICR 270

MICR 270 Study Questions to Guaranteed 100% Pass

Preview 4 out of 51  pages

  • September 19, 2024
  • 51
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • MICR 270
  • MICR 270
avatar-seller
KenAli
MICR 270 Study Questions to
Guaranteed 100% Pass


Hematopoietic Stem Cell - Answer Every blood cell arises from this

Self Renewal:Ability to divide itself to replace older cells and keep the pool of stem
cells constant

Pluripotent (multipotent): can differentiate into many other cell types but once a
stem cell commits to a lineage it loses self renewal ability



Lymphoid Lineage - Answer lymphoid progenitor cells differentiate to make up
the adaptive immune system
Major cells are the T and B cells (lymphocytes)



lymphoid progenitor - Answer Ability to differentiate into B-cells (plasmocyte =
effector B-cell, Memory B-cell), T-cells (Helper T-cell, Cytotoxic T-cell, Memory T-cell),
Natural Killer Cells


Myeloid Lineage - Answer Differentiate into most cells of innate immunity



Myeloid Progenitor - Answer Differentiate into Granulocyte (neutrophil, eosinophil,
basophil, mast cell), Monocyte (macrophage), Erythrocyte, Thrombocyte



Dendritic Cell - Answer Arise from myeloid or lymphoid progenitor cells
Part of adaptive and innate immunity

,Function to capture and engulf antigens and present them to the adaptive immune cells
Various subsets



Erythrocytes and Platelets - Answer Platelets: coagulation, wound healing
and fibrinolysis
Inflammatory function influencing innate and adaptive immunity

Involved in - intervention against microbes, recruitment and promotion of innate
effector cell functions, modulate antigen presentation, enhance adaptive immunity

Erythrocytes and Platelets:
formed during hematopoiesis


Monocyte and Macrophage - Answer - are phagocytes
- Monocytes are in the blood
- macrophages are in the tissues

- when monocytes enter tissues they become bigger, increase complexity of intracellular
structures, are better at phagocytosis
- macrophages are the most efficient phagocytes


Mast Cell - Answer - located in tissues
- are granulocytes with granules containing histamine
- similar to basophils
- role in allergy development


Neutrophil - Answer - most abundant leukocyte (WBC)

- characteristics of granulocytes (polymorphic nucleus, granules containing lytic
enzymes) and phagocytes (ability to engulf and absorb bacteria)
- First to arrive at inflammation site and live a few days

,Basophil - Answer - non-phagocytic granulocyte
- polymorphic nucleus and granules with pharmacologically active substances
- largest granules
- least common granulocyte
- similar to mast cells
- role in allergy development


Eosinophil - Answer - phagocytic (but minor phagocytic role)
- Polymorphic nucleus and granules able to damage parasitic membranes (granulocyte)
- Role in defence against multicellular parasites


Natural Killer Cell - Answer - granular lymphocytes

- granules containing perforin (create lesions in membranes) and granzymes (induce
cell death)
- can recognize tumour or infected cells
- don't have antigen-specific receptors
- distinguish and destroy abnormal cells
- part of innate immunity


T-cell - Answer - Cell mediated immunity
- Specific: one T-cell expresses many TCR that recognize the same specific antigen
- Diverse: every T-cell recognizes a different antigen
- Helper T-cell (CD4)
- Cytotoxic T-cell (CD8)

, MALT (Mucosal Associated Lymphoid Tissues) - Answer Structure: Combined
surface area of various areas in the body
Location: mucous membranes lining the digestive, respiratory and urogenital systems

Function: Initiates immune response to specific antigens encountered along mucosal
surfaces



Spleen - Answer Structure: large, ovoid, two compartments (red pulp: cords of Billroth -
fibrils and connective tissue cells with monocytes and macrophages, white pulp: filled
with macrophages, lymphocytes, T-cells, B-cells and RBC)
Location: left abdominal cavity

Function: red pulp filters blood, white pulp is the site of immune response
development against antigens in the blood



Thymus - Answer Structure: Flat, Bi-lobed, filled with thymocytes (T-cells in the thymus),
epithelial cells, dendritic cells and macrophages
Location: above the heart
Function: Site of T-cell development and maturation


Primary Lymphoid Organs - Answer Thymus and bone marrow
- Site of lymphocyte maturation
- B-cell --> Bone marrow
- T-cell --> Thymus


Secondary Lymphoid Organs - Answer Spleen, lymph nodes and MALT

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller KenAli. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $14.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

77254 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$14.49
  • (0)
  Add to cart