ABRAMS’ CLINICAL DRUG THERAPY RATIONALES FOR
NURSING PRACTICE 12TH EDITION GERALYN FRANDSEN’s
TESTBANK/COMPLETE GUIDE 2024-2025/ALL CHAPTERS 1-61
,Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral
paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
CORRECT ANSWER:-B
EXPLANATION:->>>Medication that produce systemic effects are taken into the body,
circulated through the bloodstream to their sites of action in various body tissues, and
eventually eliminated from the body. Curative agents are given to cure a disease process. In
this case, paroxetine hydrochloride will control the symptoms but not cure the disorder.
Medication with local effects, such as sunscreen and local anesthetics, act mainly at the site
of application. Paroxetine hydrochloride is not administered parenterally. Parenteral agents
are administered subcutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been cheG
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SoBdOifOieSd.TWhaOt Mi s another name for this type of
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medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
CORRECT ANSWER:-B
EXPLANATION:->>>Semisynthetic medication (e.g., many antibiotics) are naturally
occurring substances that have been chemically modified. Synthetic medication are more
standardized in their chemical characteristics, more consistent in their effects, and less
likely to produce allergic reactions. Biotechnology medication involve manipulating DNA
and RNA and recombining genes into hybrid molecules that can be inserted into living
organisms. Prototype medication are the first drug of a particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
, C. Anti-inflammatory
D. Antihypertensive
CORRECT ANSWER:-A
EXPLANATION:->>>Medication are classified according to their effects on particular
body systems, their therapeutic uses, and their chemical characteristics. Morphine is
classified as a central nervous system depressant and will produce this effect in the client. A
central nervous system stimulant increases attention and raises mood. An anti-inflammatory
agent decreases inflammation at the site of tissue or joint inflammation. An antihypertensive
agent reduces blood pressure.
PTS: 1 REF: p. 3, Drug Classifications and Prototypes
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs to which
drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
CORRECT ANSWER:-C
EXPLANATION:->>>The generic namGeRoA fteDnEiS
ndBicOaO
teS
sTth.
e CdrOug group (e.g., medication
with generic names ending in “cillin” are penicillins). Selective serotonin reuptake
inhibitors are medications
that have antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics
are medications that increase urine output; diuretic is a broad classification, not a generic
name. ACE inhibitor is the broad classification for the angiotensin receptor blockers, not the
generic name.
PTS: 1 REF: p. 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug
Administration
CORRECT ANSWER:-D
, EXPLANATION:->>>The Food and Drug Administration approves medication for over-
the-counter availability, including the transfer of medication from prescription to OTC
status, and may require clinical trials to determine the safety and effectiveness of OTC use.
The Public Health Service is regulated by the state to maintain the health of individual
citizens of the state. The Federal Trade Commission regulates imports and exports
throughout the nation. The Occupational Safety and Health Administration regulates safety
within the workplace.
PTS: 1 REF: p. 4, Prescription and Nonprescription
Medication OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
CORRECT ANSWER:-B
EXPLANATION:->>>The Comprehensive Drug Abuse Prevention and Control Act
regulates the manufacture and distribution of narcotics, stimulants, depressants,
hallucinogens, and anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised
and broadened FDA powers and responsibilities, giving the FDA control over drug safety.
The Harrison Narcotic Act restricted the importation, manufacture, sale, and use of opium,
cocaine, marijuana, and other medication that the act d e f i Gn eRd AaDs E
naSrcBoO
tiO
csS
.TTh.eCSOhM
erley
Amendment of 1912 prohibited fraudulent claims of drug effectiveness.
PTS: 1 REF: p. 4, Prescription and Nonprescription
Medication OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nurse practitioner is responsible for maintaining an accurate count and record of the
controlled substances on the nursing division. This nursing action is regulated by which
U.S. law or agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
CORRECT ANSWER:-C
