Anovulatory AUB O - Answer No luteal phase (or corpus lutetium) hormone imbalance,
and breakthrough bleeding
amenorrhea - Answer No menses, Primary - never had menses by age 16 vs Secondary
lack of menses for 3 cycles
Ovulatory AUB - Answer Included amenorrhea to heavy bleeding, HPOA intact and
hormones are normal. Cyclic, regular. Varying bleeding.
Endometrial AUB E - Answer Predictable, cyclic and heavy bleeding. Consider
infections = endometritis and dx of exclusion.
Iatrogenic AUB I causes - Answer Medications/devices
- hormonal contraception
- antidepressants
Anovulatory Phase - Answer Without a resulting corpus luteum to produce progesterone
enough to support the uterine lining during an anovulatory cycle, the uterine lining is
shed causing anovulatory bleeding or breakthrough bleeding. This differs from an
ovulatory menstrual cycle in which the uterine lining sheds as a result of the no
conception and the waning corpus luteum.
Targeted HX for AUB - Answer HPI
Pregnancy Risk
Age
Meds
Menstral hx
Eating habits
Exercise
Contraception
Change in body wt
HA
, Menopausal symptoms
GYN procedures
Pelvic inflammatory Hx
Lab testing - Answer hCG
CBC
Coagulation studies
Iron studies
Hormones - FSH, LH, progesterone and testosterone
Thyroid studies
Adrenal studies
Prolactin
PAP test
Wet mount
Endometrial biopsy
Dx imaging - Answer Transvaginal US (day 4 or six of cycle)
Hysteroscopy - direct visitation and biopsy
MRI
CT scan
Expected level of Progesterone in Anovulatory phase - Answer less than 10
Best time to draw progesterone to detect anovulatory bleeding - Answer You want to
draw progesterone levels when they are expected to be at peak. This typically occurs
during the luteal phase between days 22-24. Low levels at this time would suggest
anovulatory bleeding.
Goals of Tx for AUB - Answer 1. Normalize beeding
2. correct anemia
3. prevent or diagnose cancer
4. restore quality of life
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