NUR 314 Intro to Pharmacology Exam Study Guide
Pharmacology - Correct Answer the study of drugs and their interactions with living systems
Drug - Correct Answer Comes from pants, animals, minerals, synthetic compounds, genetically altered compounds
Turn on a body's response, turn off a respons...
NUR 314 Intro to Pharmacology Exam Study
Guide
Pharmacology - Correct Answer the study of drugs and their interactions with living systems
Drug - Correct Answer Comes from pants, animals, minerals, synthetic compounds, genetically
altered compounds
Turn on a body's response, turn off a response, increase a response, decrease a response, or block a
response
Used to cure, diagnose, treat/relieve, or prevent
Clinical pharmacology - Correct Answer the study of drugs in humans and their clinical use
Therapeutics - Correct Answer The use of drugs to diagnose, prevent, or treat disease or to prevent
pregnancy; the medical use of a drug
Why the drug is prescribed.what we want the drug to do
Pharmacokinetics - Correct Answer what the body does to the drug
The four phases of pharmacokinetics - Correct Answer Absorption (occurs in the blood via GI tract,
skin, mucous membranes, or direct injection); Distribution (transport of the drug from the site of
absorption to the site of action);
Metabolism (occurs in the liver, kidneys, or site of action); and
Excretion (occurs in the kidneys, bile, or stool)
Pharmacodynamics - Correct Answer what the drug does to the body
Plasma drug level - Correct Answer drug level measured in the pt's blood
Minimum effective concentration - Correct Answer minimum concentration of drug in plasma
required to produce the therapeutic effect
Toxic concentration - Correct Answer level of harmful effects that a drug can have that may cause
permanent injury or death
, Therapeutic range - Correct Answer dosage range or blood plasma or serum concentration usually
expected to achieve desired therapeutic effects
Drug potency - Correct Answer how many particles of a drug (mcg, mg, etc.) are needed to produce
the intended/desired effect
Maximal drug efficacy - Correct Answer (Emax) the largest effect that a drug can produce
Controlled substance - Correct Answer drugs that are categorized by federal law according to
therapeutic usefulness and potential for abuse
Agnoist drug-receptor interaction - Correct Answer molecule that activates receptors; something that
fits the receptor and CREATES the action that we are looking for
Antagonist - Correct Answer blocks the receptor site to PREVENT endogenous substances, or other
drugs, from binding
Partial agonist - Correct Answer molecule that produces a response but not as great as a full agonist
(buprenorphine)
Receptor - Correct Answer the specific target site for a drug to bind, usually on the cell membrane
surface, but may be inside the cell
Ideal drug - Correct Answer Low cost, reversible, predictable, easy to give, no drug interactions,
simple generic name
Drug distribution - Correct Answer transportation of a drug to its site of action from its site of
absorption
affected by: blood flow tissues, drug movement between vasculature and cells, lipophillicity,
hydrophillicity, and protein binding
Drug absorption - Correct Answer getting the drug from its location of administration to the
bloodstream for circulation
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