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NURS 611 EXAM 1 PATHO ACTUAL EXAM AND TEST BANK COMPLETE 500 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES GRADED A+ (MARYVILLE UNIVERSITY

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NURS 611 EXAM 1 PATHO ACTUAL EXAM AND TEST BANK COMPLETE 500 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES GRADED A+ (MARYVILLE UNIVERSITY) What is Apoptosis? - ANS-A programmed cell death Aneuploid cells - ANS-Cells that do not contain a multiple of 23 chromosomes. Aneuploi...

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  • September 19, 2024
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  • NURS 611 1 PATHO ACTUAL TES-BANK
  • NURS 611 1 PATHO ACTUAL TES-BANK
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NURS 611 EXAM 1 PATHO ACTUAL
EXAM AND TEST BANK
COMPLETE 500 QUESTIONS AND
CORRECT DETAILED ANSWERS
WITH RATIONALES GRADED A+
(MARYVILLE UNIVERSITY)
What is Apoptosis? - ANS-A programmed cell death

Aneuploid cells - ANS-Cells that do not contain a multiple of 23
chromosomes.

Aneuploid cell containing 3 copies of 1 chromosome - ANS-Trisomic
-condition called trisomy

Most well know example of aneuploidy in an autosome is: - ANS-
trisomy of the 21st chromosome

Trisomy of 21st Chromosome also known as - ANS-Down Syndrome

Characteristics of Downs syndrome - ANS-IQ 25-70
Facial features: low nasal bridge, protruding tongue, and flat low-set
ears

Penetrance - ANS-The percentage of individuals with a specific
genotype who also exhibit the expected phenotype.

,An example of Penetrance would be what disease? - ANS-
Huntington disease

Incomplete penetrance - ANS-Individuals who have disease causing
allele may not exhibit the disease phenotype at all, even though the
allele and the associated disease may be transmitted to the next
generation

Huntington disease is autosomal ____ - ANS-dominant

Huntington's features are - ANS-Progressive dementia and
increasingly uncontrolled movement of the limbs.

Key feature of Huntington's - ANS-S/s not usually seen until age 40
or later

Example of age dependent penetrance - ANS-Huntington disease

Expressivity - ANS-The extent of variation in phenotype associated
with a particular genotype.

Well-known example of variable expressivity in an autosomal
dominant disease is - ANS-Type 1 neurofibromatosis, or von
Recklinghausen disease

What is necrosis? - ANS-Death of most or all of the cells in an organ
or tissue due to disease, injury, or failure of the blood supply.

Characteristics of tissue necrosis - ANS-1) Rapid loss of of the
plasma membrane structure
2) Organelle swelling
3) Mitochondrial dysfunction

, Hypoxia - ANS-What is the #1 major cause of cellular injury leading
to necrosis. (especially the kidney and heart)

What is hypertrophy? - ANS-Is an increase in the size of cells

Physiologic hypertrophy - ANS-Hypertrophy of myocardial cells
such as in endurance training

Pathologic hypertrophy - ANS-Occurs secondary to HTN

What is Hyperplasia - ANS-Increase in the number of cells

Pathological hyperplasia - ANS-Endometrial hyperplasia

Compensatory hyperplasia - ANS-Removal of 70% of the liver- can
regenerate in about 2 weeks

What is Metaplasia - ANS-Replacement of cells

Example of Metaplasia - ANS-Normal columnar ciliated epithelial
cells of the brohchial lining have been replaced by stratified
squamous epithelial cells

During ischemia, what effect does the loss of the ATP levels have on
cells? - ANS-Reduction in ATP levels causes the plasma
membrane's sodium-potassium pump and sodium-calcium
exchange to fail, which leads to an intracellular accumulation of
sodium and calcium and diffusion of potassium out of the cell.
Sodium and water then can enter the cell freely, and cellular
swelling results.

Free radicals play a major role in the initiation and progression of
which diseases? - ANS-These reactive oxygen species play major

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