Exam (elaborations)
NURS 8024 Pharm Exam 3 (antimicrobial part 2)fully solved
- Course
- Institution
NURS 8024 Pharm Exam 3 (antimicrobial part 2)fully solved
[Show more]
Content preview
NURS 8024 Pharm Exam 3 (antimicrobialpart 2)
Bacterial protein synthesis inhibitors - correct answer ✔✔Clindamycin
Clindamycin - correct answer ✔✔Time dependent killing
Inhibits protein synthesis
Bacteriostatic
90% bioavailability
Clindamycin mechanism of resistance - correct answer ✔✔Altered target sites
Active efflux (pushes drug out of the cell)
Clindamycin ADE - correct answer ✔✔GI upset
Skin rash
Neutropenia
Superinfections such a c diff pseudomembranous
- don't use if patient has history of c diff
Clindamycin indications - correct answer ✔✔Gram positive
Prophylaxis of endocarditis in valve patients with PCN allergy
Oxazolidinones - correct answer ✔✔New class of bacterial protein synthesis inhibitors
Time dependent killing
Prevents formation of ribosome complex
Bacteriostatic & Bactericidal against strep
, Linezolid - correct answer ✔✔Protein synthesis inhibitor
100% bioavailability orally
30% CSF penetration
Linezolid ADE - correct answer ✔✔Hematologic
Increased thrombocytopenia risk
Anemia, neutropenia, neuropathy
Optic & peripheral neuropathy
Serotonin syndrome with SSRIs
Linezolid Indications - correct answer ✔✔Gram positive resistant
VRE, HCAP, CAP
Complicated skin & tissue infections
Off label use for TB
No resistance currently
Fluoroquinolones - correct answer ✔✔Norfloxacin (1st gen)
Ciprofloxacin & Ofloxacin (2nd gen)
Levofloxacin (3rd gen)
Moxifloxacin & Gemifloxacin (3rd gen respiratory)
Fluoroquinolones are classified by - correct answer ✔✔Generations according to antimicrobial spectra
1st Generation Fluoroquinolone - correct answer ✔✔Narrow gram negative
Norfloxacin
2nd Generation Fluoroquinolone - correct answer ✔✔Broad- gram negative and gram positive
Cipro & ofloxacin
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller BravelRadon. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $21.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
62555 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now
