Exam (elaborations)
ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM 2024/2025
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ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM 2024/2025
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ONS CHEMOTHERAPY IMMUNOTHERAPYCERTIFICATE EXAM 2024/2025
Define neoadjuvant therapy - Precise Answer ✔✔Treatment is given
prior to surgery to shrink the tumor
Define adjuvant therapy - Precise Answer ✔✔Additional cancer
treatment given after the primary treatment to lower the risk that the
cancer reoccur
3 subcategories of alkylating agents: - Precise Answer ✔✔1. Nitrogen
mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas
Common alkylating agents: - Precise Answer ✔✔Cyclophosphamide
(Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: - Precise Answer ✔✔Cisplatin
(Platinol)
,Carboplatin (Paraplatin)
What is unique about nitrosoureas agents? - Precise Answer ✔✔Able to
cross the blood-brain barrier; can be effective in treating some brain
tumors
Common nitrosoureas agents: - Precise Answer ✔✔Carmustine
(BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: - Precise Answer
✔✔Carboplatin
These agents are typically categorized as highly emetogenic: - Precise
Answer ✔✔1. Alkylating agents
2. Nitrosoureas
Pre-administration labs for alkylating agents and nitrosoureas: - Precise
Answer ✔✔BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? - Precise Answer ✔✔Bladder
protectant with administration of cyclophosphamide or ifosfamide
, Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment - Precise Answer
✔✔Oxaliplatin
How do antimetabolites function? - Precise Answer ✔✔By blocking
DNA and RNA growth by interfering with enzymes needed for normal
cell metabolism
Antimetabolites work in the ___ phase. - Precise Answer ✔✔S
Common side effects of antimetabolites: - Precise Answer
✔✔Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: - Precise Answer ✔✔Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
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