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NUR3196 Exam Three Prototype Drugs Questions And Accurate Answers

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NUR3196 Exam Three Prototype Drugs Questions And Accurate Answers...

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  • September 20, 2024
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  • NUR3196 Three Prototype Drugs
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NUR3196 Exam Three Prototype Drugs Questions
And Accurate Answers

Aspirin Action

Salicylate (acetylsalicylic acid)



- inhibits prostaglandin synthesis

- anti-inflammatory, antiplatelet, antipyretic effects

- toxic serum salicylate level: greater than 300 mcg/mL

- max dose: 4g/day

Aspirin Caution

- dont take w/ other NSAIDs

- avoid last trimester of pregnancy

- don't give to children w/ flu or virus symptoms (Reye syndrome)

Aspirin side effects

- dizziness, lethargy, headache, confusion, agitation, Nausea and GI distress,
diaphoresis, dehydration

Aspirin Adverse Reactions

- tinnitus, hearing loss, hypo/hyperglycemia, reye syndrome

Aspirin Drug Interactions

- increased bleeding with anticoagulants and other NSAIDs

- hypoglycemia with oral antidiabetics

- increased gastric ulcer risk with glucocorticoids

- decreased effects of ACE inhibitors, loop diuretics

Aspirin Lab interactions

- increased PT, bleeding time, INR, uric acid

,- decreased cholesterol, T3 and T4 levels, K

Aspirin food interactions

foods with salicylates

- prunes

- raisins

- licorice

- curry

- paprika

Ibuprofen action

- propionic acid derivative

- most widely used NSAID

- highly protein bound



- inhibits COX-1 and COX-2 by blocking arachidonate binding

- used for pain, osteoarthritis, rheumatoid arthritis

Ibuprofen side/adverse effects

- drowsiness, dizziness, headache, confusion

- blurred vision, hearing loss, tinnitus, edema

- gastric distress & bleeding

- anaphylaxis

Ibuprofen drug interactions

- increased bleeding with warfarin

- increased effects with phenytoin, sulfonamides, warfarin

- decreased effect with aspirin

Celecoxib action

Nonsteroidal anti-inflammatory

, COX-2 inhibitor

Celecoxib use

- pain, osteoarthritis, rheumatoid arthritis

- painful dysmenorrhea

- migraine

celecoxib food interactions

gingko biloba may increase bleeding risk

celecoxib caution

pt's with renal and hepatic dysfunction

celecoxib side/adverse effects

-headache, dizziness, sinusitis

-N/V/D

-GI bleeding

-HTN

-Hearing loss

-Anaphylaxis

Infliximab action

immunomodulator

tumor necrosis factor blocker

infliximab uses

-psoriasis

-rheumatoid arthritis

- ulcerative colitis

-crohn's diseases

-given thru IV only

infliximab caution

pt's with hepatic dysfunction, bone marrow suppression, DM, COPD

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