Inflammation is. -Answer a nonspecific defense system of the body
What could cause inflammation? -Answer physical trauma, exposure to noxious
chemicals, extreme temperature, entry of pathogenic organisms, or cell death
What are the cardinal signs of inflammation? -Answer swelling, pain, warmth, and
redness
Acute inflammation is marked by a sudden onset. Symptoms disappear after how many
days? -Answer 8-10 days
What two examples of chronic inflammation are? - Answer Systemic Lupus
Erythmatosus (SLE) and Rheumatoid Arthritis (RA)
Chemical mediators of inflammation include. - Answer histamine, leukotrienes,
bradykinin, complement, and prostaglandins
Histamine is a major chemical mediator of inflammation and is stored in. - Answer mast
cells.
Histamine does what to local blood vessels? - Answer dilates them
Anaphylaxis is. - Answer a life-threatening allergic response hat may result in shock or
death.
Bradykinin functions. - Answer vasodilator similar to histamine
,Complement functions. - Answer to neutralize or destroy an antigen; stimulates release
of histamine.
C-reactive protein. - Answer is an early marker of inflammation.
Cytokines function to. - Answer mediate and regulate immune and inflammatory actions
Histamine functions as a. - Answer vasodilator, smooth muscle constrictor, tissue
sweller
Leukotrienes function. - Answer similarly to histamine
Prostaglandins. - Answer increase capillary permeability, attract white blood cells,
cause pain, induce fever.
Inflammation is not a disease, it. - Answer indicates an underlying problem
The two types of drug classes for nonspecific inflammation are the. - Answer
non-steroidal anti-inflammatory (NSAIDs) and corticosteroids.
Due to their serious long term effects. - Answer corticosteroids are only used short term
for acute inflammation.
NSAIDs exhibit both. - Answer anti-pyretic and analgesic effects as well
NSAIDs act by inhibiting. - Answer the synthesis of prostaglandins.
NSAIDs block inflammation by. - Answer inhibiting COX, an enzyme that synthesizes
prostaglandins
, COX-1. - Answer reduces gastric acid secretion, promoting renal blood flow, and
regulating smooth muscle tone in the blood vessels.
COX-2 is formed. - Answer only after injury and promotes inflammation.
Most adverse effects from ibuprofen and aspirin are due to. - Answer the blocking of
COX-1
Aspirin belongs to the chemical family called. - Answer salicylates
Aspirin is a potent inhibitor of. - Answer thromboxane which is secreted by platelets
Salycism is a syndrome that includes symptoms such as. - Answer tinnitus, dizziness,
headache, and excessive sweating.
Children under 19 should never be administered aspirin if they have signs of fever, flu,
or chicken pox for risk of. - Answer Reye's syndrome
Ibuprofen and a lrage number of ibuprofen like drugs are. - Answer NSAIDs
Aspirins work by. - Answer inhibiting both COX-1 and COX-2 REVERSIBLY
The most common side effects of NSAIDs are. - Answer nausea and vomiting.
Patients with CKD typically receive. - Answer acetaminophen for pain or fever rather
than NSAIDs
What is the only COX-2 inhibitor still on the market? - Answer Celebrex
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