Exam (elaborations)
AMR EXAM 1 TEST 2 QUESTIONS AND ANSWERS
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AMR EXAM 1 TEST 2 QUESTIONS AND ANSWERS
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Name: Score:62 Multiple choice questions
Definition 1 of 62
Inhibits bacterial growth
Bacteriostatic
Rifampin
Vancomycin
Bacteriocidal
Definition 2 of 62
-Aromatic ring bridged by aliphatic chain
-Binds to RNA polymerase
-Simple steric block
Lipopeptides
Sulfa-Drugs
Bacitracin
Rifampin
Definition 3 of 62
-Kills specific organism
-Used when bacteria known
Broad Spectrum
Current Problem
Narrow Spectrum
Trimethoprim
,Definition 4 of 62
-Caps D-ala-D-ala
-Stops crosslinking
-Last resort antibiotic
Bacitracin
Cycloserine
Vancomycin
Macrolides
Definition 5 of 62
-Prodrug
-Gerhard Dumagk (1932)
-Used to treat Roosevelt Jr's son in 1936
-Inhibit DHPS
Oxozolidinones
Quinolones
Bacitracin
Sulfa-Drugs
Definition 6 of 62
Infection acquired from a healthcare setting
Current problem
Hospital (nosocomial)-acquired infection
Antibiotic use in farming
Broad spectrum
,Definition 7 of 62
-90% don't make it to clinical trials
-Over $2 billion in costs
-Takes 10-20 years to make antibiotic but only 8 years to develop resistance
Antibiotic use in farming
Aminoglycosides
Antimicrobial Resistance
Antibiotic Challenge
Definition 8 of 62
-Humans
-Food animals
-Pets
Alexander Fleming
Major reservoirs of AMR
RNA Synthesis Inhibitors
Folic Acid Synthesis Inhibitors
Definition 9 of 62
-Originally used as antidepressants
-Bind to 50s subunit
-Inhibits initiation complex
Aminoglycosides
Oxozolidinones
Cycloserine
Quinolones
, Definition 10 of 62
-Air
-Soil
-Water
Antibiotic use in farming
RNA Synthesis Inhibitors
Environmental transmission
Cell Membrane Disruptors
Definition 11 of 62
Infection acquired from communal setting
Community-acquired infection
Local infection
Iatrogenic infection
Hospital-acquired infection
Definition 12 of 62
-Bind to 23s subunit of 50s ribosome
-Bind to proximal end of peptide exit tunnel
-Peptidyl transferase inhibition
Aminoglycosides
Lipopeptides
Macrolides
Bacitracin
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