Exam (elaborations)
WOCN Refractory Wounds: Questions & Solutions
- Course
- Institution
WOCN Refractory Wounds: Questions & Solutions
[Show more]
Seller
Follow
Studyhall
Reviews received
Content preview
WOCN Refractory Wounds: Questions & SolutionsRole of protease inhibitors Right Ans - MMPs are enzymes that control
levels of growth factors and cytokines
Roll of protease inhibitors Right Ans - Some promote inflammation, others
reduce inflammation
Role of protease inhibitors Right Ans - Persistent high levels of pro-
inflammatory MMPs characteristic of non healing wounds
MMPs Right Ans - Most are pro inflammatory
Protease inhibitors - mechanism of action Right Ans - -Attract/bind MMPs
to dressing (ORC)
-reduce MMP production (dressings have PHI)
-Botton line is to reduce levels of MMPs to reduce interference in repair
(Data supports venous, pressure, and diabetic wounds)
Example dressings used in protease inhibitors Right Ans - Promogram,
prisma, puracol, puracol plus are the most common
Acellular matrix dressings Right Ans - -Provides scaffolding for cell
(fibroblasts) migration and attachment (to the dressing)
-Provides cellular communication
-Provides proliferative signals to cells
What do matrix dressings consist of? Right Ans - Collagen, glycoproteins,
growth factors.
Acellular matrix dressings Right Ans - Dressings that provide structure
Types of Acellular Dressings Right Ans - Porcine, bovine, avian, or cadaver
source dressings
Areas studied in RCT that show limited evidence in Acellular matrix dressings
Right Ans - Leg and pressure ulcers, surgical wounds
, 2 types of matrix dressings used in abdominal wall reconstruction Right
Ans - Modified an Unmodified
Unmodified matrix dressings Right Ans - -Non cross linked
-7-14 days for vascularization and granulation tissue
-provides support only
-resistance to bacteria
- monitor for adherence or non adherence
Modified matrix dressing Right Ans - -cross-linked
-provides strength and resistance to bacteria
-takes 4 weeks or more for vascularization (pink to red)
-monitor for adherence or non adherence
Which active dressing does not have living cells? Right Ans - Acellular
matrix dressings in abdominal wall reconstruction
Bioengineered skin substitutes Right Ans - Matrix dressings with living
cells embedded
Bioengineered skin substitutes Right Ans - Derived from neonatal foreskin
or amniotic membrane
living cells Right Ans - Need to minimize antibody and antigen response
Etiologic factors that can lead to a refractory wound Right Ans - -
Unrelieved pressure
-Inadequate circulation
-Inaccurate diagnosis
Cellular factors that can lead to a refractory wound Right Ans - -Low levels
of growth factors
-High-level of MMP's
Local factors that can lead to a refractory wound Right Ans - -closed wound
edges
-Traumatic dressing changes
-High bacterial burden
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Studyhall. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $9.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
78998 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now