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2024 NUR 251 PHARMACOLOGY TEST 1 EXAM WITH CORRECT ANSWERS
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2024 NUR 251 PHARMACOLOGY TEST 1 EXAM WITH CORRECT ANSWERS
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2024 NUR 251 PHARMACOLOGYTEST 1 EXAM WITH CORRECT
ANSWERS
Drugs have many different effects on the body including - CORRECT-
ANSWERS(1) Therapeutic effects
(2) Side effects
(3) Adverse effects
(4) Toxic effects
Pharmacology - CORRECT-ANSWERSStudy of chemicals that alter the
function of living organisms.
Drugs can be used to: - CORRECT-ANSWERS1. Prevent disease
2. Diagnose Disease
3. Cure disease
4. Treat symptoms of disease
Plant Alkaloid description - CORRECT-ANSWERS1. Vinca genus plant
2. Cell cycle specific
3. Stops mitosis
Plant Alkaloid uses - CORRECT-ANSWERSHodgkin's disease
Acute Lymphoblastic Leukemia (ALL)
Plant Alkaloid toxic effects (5) - CORRECT-ANSWERS1. Infiltration can cause
severe tissue damage.
2. Peripheral nerve toxicity
3. Possibly toxic in patients with hepatic impairments.
4. Intrathecal administration is lethal.
5. Only given by vein.
generic name for Oncovin - CORRECT-ANSWERSVincristine
Vincristine (Oncovin) - CORRECT-ANSWERSPlant Alkaloid
Alkylating Agents description (3) - CORRECT-ANSWERS1. Developed from
mustard gas agents.
,2. Interfere with cell division and structure of DNA during all phases of cell
cycle.
3. Used with variety of malignancies.
Alkylating Agent toxic effect - CORRECT-ANSWERS1. Huge risk for bone
suppression.
2. N/V so increase fluids
3. Issues with peripheral neuropathy
4. Watch for infiltration - extravasation.
generic name for Cytoxan - CORRECT-ANSWERSCyclophosphamide
generic name for Platinol - CORRECT-ANSWERSCisplatin
Cyclophosphamide (Cytoxan) - CORRECT-ANSWERS1. Take on an empty
stomach but increase fluids.
2. May cause cystitis
Cisplatin (Platinol) - CORRECT-ANSWERS1. Used for both hematological and
solid cancers.
2. IV hydration
3. N/V, nephrotoxicity, ototoxicity
4. Check renal function.
Anti-tumor / Cytotoxic antibiotics - CORRECT-ANSWERS1. Bind to DNA and
block DNA and RNA trancrtiption
Anti-tumor / Cytotoxic antibiotics use - CORRECT-ANSWERSLeukemia, Cancer
of Breast, lung, and ovary
Anti-tumor / Cytotoxic antibiotics Toxic effects (6) - CORRECT-ANSWERS1.
Bone marrow suppression
2. GI upset
3. Cardiotoxicity
4. Tissue necrosis with IV infiltration
5. Alopecia
6. Anemia, SOB, Increased issues with hepatic function.
6. May turn urine red
generic name for Adriamycin - CORRECT-ANSWERSDoxorubicin
Doxorubicin (Adriamycin) - CORRECT-ANSWERSAnti-tumor / Cytotoxic
antibiotics
Hematopoietic drugs - CORRECT-ANSWERS1. Do not treat cancer
2. Treat anemia
,3. Given SubQ for IV
Hematopoietic drugs uses - CORRECT-ANSWERSFor renal failure, cancer, HIV
Hematopoietic drugs - Nursing implications - CORRECT-ANSWERS1. Check
blood counts
2. May cause N/V/D
3. Check blood pressure as increased RBC can cause increased BP
Hematopoietic drugs side effects - CORRECT-ANSWERSStroke, heart attack
and death if hemoglobin gets too high.
generic name for Epogen - CORRECT-ANSWERSEpoetin Alfa
Epoetin Alpha (Epogen) - CORRECT-ANSWERSHematopoietic drug
Colony Stimulating Factors - CORRECT-ANSWERS1. Promotes proliferation,
differentiation and activation of cells that make granulocytes.
Colony Stimulating Factors uses - CORRECT-ANSWERS1. Prevent infection
2. Stimulate Arteriole growth
3. Patients who have neutropenia due to chemo
Colony Stimulating Factors side effects - CORRECT-ANSWERSBone pain,
redness at injection site
Colony Stimulating Factors nursing implication - CORRECT-ANSWERS1. Give
24 hours after chemo.
2. Avoid infections
G-CSF / Neupogen generic name - CORRECT-ANSWERSFilgrastim trade name
Filgrastim (G-CSF / Neupogen) - CORRECT-ANSWERSColony Stimulating
Factor drug
Interferon description (6) - CORRECT-ANSWERS1. Biological response
modifiers
2. Bind to specific cell surface receptors
3. Alter intra-cellular activities
4. Boost the immune system and prevent virus from entering cells
5. Anti viral and anti neoplastic in effect.
6. Inhibits viral replication by reprogramming virus.
Interferon use - CORRECT-ANSWERShairy cell leukemia, Kaposi's sarcoma,
chronic hepatitis
, Interferon adverse effects - CORRECT-ANSWERSFlu like symptoms,
depression, suicide
Interferon - how it works (3) - CORRECT-ANSWERS1. inhibits viral replication
by reprogramming virus
2. prevents rapid growth of malignant cells
3. Increases cyto activity of NK cells.
Roferon - A or Intron- A generic name - CORRECT-ANSWERSInterferon Alfa 2a
or 2b trade names
Interferon Alfa 2a or 2b (Roferon-A or intron-A) - CORRECT-
ANSWERSInterferon
Monoclonal antibodies description - CORRECT-ANSWERS1. Specifically target
cancer cells and have minimal effect on healthy cells.
2. Compliance is an issue because taken at home as a pill.
Monoclonal antibodies uses - CORRECT-ANSWERS1. Rheumatoid Arthritis,
Crohn's disease, Cancer, MS, and organ transplantation
2. Neutralizes activity of tumor necrosis factor alpha
Monoclonal antibodies Adverse effects - CORRECT-ANSWERS1. Fewer
adverse effects than traditional anti neoplastic meds.
2. Flu like symptoms
3. Varies with drug.
generic name for Remicade - CORRECT-ANSWERSInfliximab
Infliximab (Remicade) - CORRECT-ANSWERS1. Monoclonal Antibody
Infliximab (Remicade) uses - CORRECT-ANSWERS1. For arthritis
2. Tumor necrosis factor - A cytokine - something that prevents inflammation
from happening.
Interleukins description - CORRECT-ANSWERS1. Activates cellular immunity
2. Inhibits tumor growth
3. Prevents rapid growth of malignant cells
Proleukin generic name - CORRECT-ANSWERSAldesleukin trade name
Aldesleukin (Proleukin) - CORRECT-ANSWERSInterleukin drug
Interleukin uses - CORRECT-ANSWERS1. Renal cancer
2. Melanoma
3. HIV
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