Predisposing factors for Asthma - Answer Genetic predisposition: family hx of
allergies/asthma
Obesity - now recognized as a risk factor
Atopy - strongest predictor of asthma, defined as the genetic tendency to develop
allergic diseases such as allergic rhinitis, asthma and atopic dermatitis
Asthma - Tx of acute exacerbation - Answer SABA- repeat Q20min x 3
May need to continue SABA q3-4hrs for 24-48 hours
Continue/adjust regular control medications
Short course of oral corticosteroids
Assess adherence to medication regimen
Assess immunization status
, Asthma - when to refer to hospital - Answer Poor response to SABA after to tx 20 min
apart
Hypoxia - O2 sat <95% on RA
Marked breathlessness - inability to speak in sentences
Use of accessory muscles
Changes in alertness
PEF of <50% of personal best
Asthma - Oral corticosteroid dosing - Answer Children - 1-2mg/kg/day
Adults - 40-60mg/day
May be given daily or BID in divided doses.
Duration 3-10 days or until symptoms resolve
Poor compliance with meds = daily
Significant side effects = BID
Don't take dose right before bed
No need to taper if less than 7 days
SABA - Answer Short acting Beta Agonist
Albuterol
Pirbuterol
Levalbuterol
Adverse effects - well tolerated, tachycardia, angina, and tremor.
SAMA - Answer Short acting muscarinic antagonist
Ipratropium (atrovent)
Adverse effects - dry mouth, irritation of the pharynx. May raise intraocular pressure in
glaucoma.
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