knowledge of how drugs are administered, to where they travel in the body, to the actual
responses produced
therapeutics - concerned with the prevention of disease and treatment of suffering
pharmacotherapy - also referred to as pharmacotherapeutics
use of drugs to treat diseases and relieve human suffering
drug - a chemical agent that has the ability to produce biologic responses within the
body.
can be desirable/therapeutic or undesirable/adverse
medication-Answer a drug is call this after it is administered
biologics-Answer agents naturally produced in animal cells, by microorganisms, or the
body itself
ex: hormones, monoclonal antibodies, natural blood products and components,
interferons, and vaccines
complementary and alternative medicine (CAM) therapies-Answer these includes
natural plant extracts, herbs, vitamins, minerals, dietary supplements, and other
techniques out of the realm of conventional therapeutics
,ex: body based practices such as physical therapy, manipulations, massage,
acupuncture, hypnosis, and biofeedback
therapeutic classification - Answer organizing drugs based on their therapeutic
usefulness in treating particular diseases or disorders
ex: influence blood clotting= anticoagulant
lower blood cholesterol= antihyperlipidemic
pharmacologic classification - Answer refers to the way a drug works at the molecular,
tissue, or body system level and based on their mechanism of action
mechanism of action - Answer the pharmacologic classification addresses this:
how a drug produces its physiological effect in the body
prototype drug - Answer well-understood drug model with which other drugs in its
representative class are compared
Chemical name-the name assigned using the standard or official nomenclature
established by the International Union of Pure and Applied Chemistry (IUPAC); a drug
has only 1 chemical name, which is helpful in predicting its properties
Ex: diazepam= 7-chloro-1, 3 dihydro-1-metyl.etc
Generic name-the name assigned by the U.S. Adopted Name Council
With a few exceptions, these are less complicated and easier to remember than
chemical names
trade name-named by the company marketing the drug
, can have many generic substance [ibuprofen] has many trade name: advil, midol 200
combination drug-contains more than one active generic ingredient which poses a
problem in trying to match one generic name
bioavailability-the physiological ability of the drug to reach its target cells and produce
its effect (reach in the bloodstream and target tissue)
Pharmacoeconomics - question a sub-discipline of health economics has helped in
situations involving broader application of a particular type of drug therapy (issues
dealing with cost of medications)
ex: some groups of patients may benefit from the development of a particular class of
drug. Decisions are often based on cost, insurance, etc
formulary - question first standard commonly used by pharmacists that is a list of drugs
and drug recipes
pharmacopeia a medical reference that summarizes standards of drug purity, strength,
and directions for synthesis
excipients the inactive ingredients in drugs and dietary supplements
US Food and Drug Administration (FDA) an agency created within the US Department of
Health and Human Services to regulate prescription and over the counter drugs
black box warnings- named after the black box appearing around drug safety
information located within package inserts, eventually became on of the primary alerts
of identifying extreme adverse drug reactions discovered during and after review
process
preclinical investigation- involves extensive laboratory research
first phase of approval of drugs
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