All except _________ selective agents and _______________ inhibit platelet
aggregation. Right Ans - COX-2 ; Nonacetylated Salicylate
MOA for COX-2 Selective Inhibitors (Coxibs) Right Ans - Inhibits
prostaglandin synthesis at sites with inflammation without affecting COX-1
(GI, Kidney, Plus)
Name the four MOA of Aspirine: Right Ans - 1. Anti-Inflammatory Effects
(Prostaglandin, thromboxjnes, bradykinin and histamine)
2. Analgesic Effect
3. Antipyretic Effect
4. Antiplatelet Effect
ASA can cause _______________ of _____________ for the _______________ of the platelet.
Right Ans - Inactivation ; COX-1 ; Life
First line of treatment for MSK Pain? Right Ans - Rest
Ice
Compression
Elevate
First line medication TX for MSK pain? Right Ans - Acetaminophen
Second line medication TX for MSK Pain? Right Ans - NSAIDS
The NP should be concerned with comorbid conditions when prescribing
NSAIDs especially ______________ and ____________. Right Ans - Renal ; Liver Fx
Name four TX for Osteoarthritis: Right Ans - Tylenol (NUMBER ONE)
NSAIDs
COX-2 Inhibitors
Intraarticular Injection of Steroids
What is the name for the urate crystals in joint? Right Ans - Tophi
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