100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
NAPLEX antibiotics Exam Questions and Answers fully solved 100% $11.09   Add to cart

Exam (elaborations)

NAPLEX antibiotics Exam Questions and Answers fully solved 100%

 0 view  0 purchase
  • Course
  • NAPLEX
  • Institution
  • NAPLEX

MIC -ANSWER- lowest drug concentration that prevents visibile microbial growth in 24 hours gram (+) bacteria species -ANSWER- staph, strep, EC, clostridium, listeria which antibiotics exhibit time-dependent killing? -ANSWER- penicillins, cephalosporins how can you increase the killing of a...

[Show more]

Preview 3 out of 16  pages

  • September 23, 2024
  • 16
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NAPLEX
  • NAPLEX
avatar-seller
IMORA
NAPLEX antibiotics Exam Questions and
Answers fully solved 100%


MIC -ANSWER- lowest drug concentration that prevents visibile microbial growth in 24
hours

gram (+) bacteria species -ANSWER- staph, strep, EC, clostridium, listeria

which antibiotics exhibit time-dependent killing? -ANSWER- penicillins, cephalosporins

how can you increase the killing of a time-dependent antibiotic? -ANSWER- dose more
frequently, extend the infusion time

example of concentration-dependent antibiotic? -ANSWER- aminoglycosides
(gentamicin, tobramycin, amikacin)

what are the bacteriostatic antibiotics (protein synthesis inhibitors)? -ANSWER-
macrolides
aminoglycosides
tetracyclines
clindamycin
linezolid
quinupristin, dalfopristin

what is the MOA of penicillins, cephalosporins, carbapenems, and vancomycin? -
ANSWER- cell wall inhibitors - bactericidal

what general ADRs are the black box warning for aminoglycosides? -ANSWER-
nephrotoxicity and neurotoxicity

what are the aminoglycosides? -ANSWER- tobramycin
gentamicin
amikacin

what type of nephrotoxicity do aminoglycosides cause? -ANSWER- ATN - acute tubular
necrosis

what weight do you use to dose aminoglycosides? -ANSWER- IBW (unless TBW is
less)
*use ABW if obese ( > 30% IBW)

what organisms are aminoglycosides mainly active against? -ANSWER- gram (-): GNR,
PA

,extended interval dosing of the aminoglycosides? -ANSWER- gent/tobra: 4-7 mg/kg
amikacin: 15-20 mg/kg
*draw random level within 6-16 hours after dose

adjust body weight (ABW) formula? -ANSWER- IBW + [0.4(TBW - IBW)]

desired trough (traditional dosing) for gent/tobra? peak? -ANSWER- trough: < 2 mcg/mL
peak: 5-10 mcg/mL

amoxicilin brand name -ANSWER- Amoxil

what organisms do the penicillins cover? -ANSWER- mainly gram (+), some gram (-)

which penicillin is the DOC in acute otitis media? -ANSWER- amoxicillin

which penicillin has activity against PA? -ANSWER- piperacillin

which penicillins do not require renal dosing? -ANSWER- nafcillin
oxacillin
dicloxacillin

Does Amoxil suspension need to be refrigerated? -ANSWER- no - stable for 14 days at
room temperature

how do you need to take Pen VK? -ANSWER- on an empty stomach

what IV fluid is ampicillin only compatible with? -ANSWER- NS

what are the main penicillin drug interactions? -ANSWER- probenacid, allopurinol -
increased penicillin levels
may decrease levels of oral contraceptives

what type of killing do cephalosporins exhibit? -ANSWER- time-dependent

what are the first generation cephalosporins? -ANSWER- cefazolin and cephalexin

what organisms are every cephalosporin active against? -ANSWER- strep/staph and
GNR

which cephalosporins are active against PA? -ANSWER- cefepime and ceftazidime

cefazolin brand name? -ANSWER- Kefzol

cephalexin brand name? -ANSWER- Keflex

ceftriaxone brand name and generation? -ANSWER- Rocephin - 3rd gen

, cefuroxime brand name? -ANSWER- Ceftin, Zinacef

what is the lone 4th generation cephalosporin? -ANSWER- cefepime (Maxipime) - 1-2 g
Q8-12

what generation is ceftaroline (Teflaro) in? -ANSWER- 5th

what are the main side effects of cephalosporins? -ANSWER- seizures with
accumulation
increased LFTs
GI upset, diarrhea
bone marrow suppression

which cephalosporins DO NOT require renal dose adjustments? -ANSWER- ceftriaxone
(Rocephin) - 3rd generation

what are the main drug interactions of cephalosporins? -ANSWER- probenacid,
allopurinol - increased levels of cephalosporins

may decrease effectiveness of oral contraceptives

What type of killing do carbapenems exhibit? -ANSWER- time-dependent bactericidal

generic name for Primaxin? -ANSWER- imipenem / cilastatin

what organisms do the carbapenems cover? -ANSWER- everything
*ertapenem = no EC or PA
*no MRSA

Brand name for meropenem? -ANSWER- Merrem

Brand name for ertapenem? -ANSWER- Invanz

Brand name for Doripenem? -ANSWER- Doribax

can carbapenems be used in a PCN allergy? -ANSWER- NO

carbapenem drug interactions? -ANSWER- uricosuric agents (probenacid, allopurinol)
caution with seizures

MOA of flouroquinolones -ANSWER- inhibit bacterial DNA topoisomerase IV and inhibit
DNA gyrase

what type of killing to flouroquinolones exhibit? -ANSWER- concentration-dependent
bactericidal

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller IMORA. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $11.09. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

77016 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$11.09
  • (0)
  Add to cart