WOCN Refractory Wounds ExamWOCN Refractory Wounds Exam Questions With Solutions
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Course
WOCN
Institution
WOCN
WOCN Refractory Wounds Exam Questions
With Solutions
role of protease inhibitors MMPs are enzymes that control levels of growth factors and
cytokines
Roll of protease inhibitors Some promote inflammation, others reduce inflammation
Role of protease inhibitors Persistent high levels of pro-in...
WOCN Refractory Wounds Exam Questions
With Solutions
role of protease inhibitors MMPs are enzymes that control levels of growth factors and
cytokines
Roll of protease inhibitors Some promote inflammation, others reduce inflammation
Role of protease inhibitors Persistent high levels of pro-inflammatory MMPs
characteristic of non healing wounds
MMPs Most are pro inflammatory
Protease inhibitors - mechanism of action -Attract/bind MMPs to dressing (ORC)
-reduce MMP production (dressings have PHI)
-Botton line is to reduce levels of MMPs to reduce interference in repair
(Data supports venous, pressure, and diabetic wounds)
Example dressings used in protease inhibitors Promogram, prisma, puracol, puracol plus
are the most common
, WOCN Refractory Wounds Exam Questions
With Solutions
Acellular matrix dressings -Provides scaffolding for cell (fibroblasts) migration and
attachment (to the dressing)
-Provides cellular communication
-Provides proliferative signals to cells
What do matrix dressings consist of? Collagen, glycoproteins, growth factors.
Acellular matrix dressings Dressings that provide structure
Types of Acellular Dressings Porcine, bovine, avian, or cadaver source dressings
Areas studied in RCT that show limited evidence in Acellular matrix dressings Leg and
pressure ulcers, surgical wounds
2 types of matrix dressings used in abdominal wall reconstruction Modified an
Unmodified
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