Vancomycin AE - ototoxicity, nephrotoxicity, red man syndrome
Vancomycin main danger - Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it
increases mortality
Monobactams treats - gram negative aerobic
Fosfomycin treats - enterococcus and Ecoli
Aminoglycosides treat - gram negative bacilli
Aminoglycosides adverse effects - ototoxicity and nephrotoxicity
aminoglycosides peak and trough - Peak: 30 min after IV or IM
Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like
zero)
Sulfonamides MOA - inhibit folic acid synthesis
UTI drugs - 1) TMP/SMZ and nitrofurantoin
2) levofloxacin & ciprofloxacin
UTI in pregnancy - TMP/SMZ, Cipro, Levo, augmentin, cephalexin
recurrent UTI prophylaxis - TMP
Recurrent UTI other tx - SMZ 3 x week for 6 months; TMP or nitro at bedtime for 6 mos.
tetracycline absorption is impaired by - -magnesium laxative
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