NSG 520 Final Latest Update 2024-2025 Actual
Exam 400 Questions and 100% Verified Correct
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2 resources for drug shortages - CORRECT ANSWER: FDA drug shortages website
ASHP drug shortage website
3 specific properties for successful transdermal and dermal delivery - CORRECT
ANSWER: <600 Da
low melting point
large drug dose
35 year old female living with HIV presents to the infectious disease clinic with a two
week history of white plaques in her mouth and painful swallowing. She has a history of
poor adherence to antiretrovirals the doctor would like to prescribe fluconazole 100
milligrams daily for esophageal Candidiasis and asks you, the clinical pharmacist, if
tablets are the only option. You check the fluconazole monograph:
solution, IV: 100mg, 200mg, 400mg
suspension reconstituted, oral: 10mg/mL, 40mg/mL
tablet, oral: 50mg, 100mg, 150mg, 200mg
Your recommendation is
A. she will just have to deal with swallowing tablets
B. only alternative is IV solution so she will have to be admitted to the hospital
C. the pharmacy can compound an extemporaneous suspension
D. prescribe 2.5 mL of the 40 mg/mL oral suspension daily to equate 100 mg
E. prescribe 100 mL of the 10 mg/mL oral suspension daily to equate 100 mg -
CORRECT ANSWER: D
,4 advantages of liposomes for ocular delivery - CORRECT ANSWER: enhanced
bioavailability
controlled release
targeted delivery
improved efficacy
A 24 year old female is recovering in the intensive care unit after a motor vehicle
accident. She is mechanically ventilated and recently had an enteral tube placed for
enteral feedings. She is prescribed multiple medications in the team asks you if any can
be administered via the enteral tube. This is / these are general considerations
regarding enteral tube administration of medications:
A. compatibility of the medication with tube feedings
B. PH dependent dissolution of the medication
C. accuracy of medication dosing
D. all of the above - CORRECT ANSWER: D
A 65 year old male with a history of diabetes and hypertension is in the neurology
intensive care unit for observation following a cerebral vascular incident. He was given
tissue plasminogen activator TPA alteplase upon presentation to the emergency
Department. He regained a significant amount of functioning but is still experiencing
dysphasia. The team asks you, the clinical pharmacist, if his medications can be
crushed and mixed with applesauce for administration. The first stop on your literature
search is the do not crush list. The organization that maintains this list is the:
A. Institute for safe medication practices
B. Food and Drug administration
C. United States pharmacopoeia
D. American Heart Association - CORRECT ANSWER: A
accumulation of triglyceride particles at the top of an emulsion - CORRECT ANSWER:
creaming
an IV solution has a shelf life of 5 hours at room temp (25 degrees C). what is the shelf
if stored int he fridge at 5 degrees C? - CORRECT ANSWER: 5/3^((5-25)/10)
,45 hours
an oral suspension has a shelf life of 48h at 5 degrees C. what is the estimated shelf life
at room temp (25 degrees C)? Use Q value of 3 - CORRECT ANSWER: 48/3^((25-
5)/10)
5.33 hours
are the following dosage forms considered single-unit or multiple unit?
capsule
granule
pellet
tablet
mini-tablet - CORRECT ANSWER: single
multi
multi
single
multi
average skin (epidermis and dermis) thickness - CORRECT ANSWER: 2.1mm
batches of less than 25 high-risk compounded products do not require sterility testing -
CORRECT ANSWER: t
BUD for nonsterile nonaqueous formulations - CORRECT ANSWER: 6 months
BUD for nonsterile water containing oral form - CORRECT ANSWER: 14 days stored in
fridge
, BUD for water-containing topical/dermal and mucosal liquid and semisolid formulations -
CORRECT ANSWER: 30 days or the intended duration of therapy (as long as it's less
than 30 days)
BUD or exp date?
based on analytical and performance testing - CORRECT ANSWER: exp date
BUD or exp date?
chemical and physical stability of manufactured (sterile) products - CORRECT
ANSWER: exp date
circulation life for liposomes - CORRECT ANSWER: more than 5 hour half-life, long
circulation life
color changes or precipitation are indicative or which type of incompatibility - CORRECT
ANSWER: physical
creaming or cracking of lipids may occur in which scenario - CORRECT ANSWER:
lipids mixed into TPN (3-in-1)
define extemporaneous - CORRECT ANSWER: impromptu
prepared without a standard formula from an official compendium
prepared as required for a specific patient
define personalized medicine - CORRECT ANSWER: pts receive meds tailored for them
rather than the same drug at the same dose
describe the difference between adverse events and adverse drug reactions -
CORRECT ANSWER: AE have an unknown cause
ADR = drug is cause
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