NSG 533 - Module 8 Hypertension and
Artherosclerosis
What is dyslipidemia? - ANSabnormal concentrations of serum lipoproteins
What are the 3 serum lipoproteins? - ANSVery Low density lipoproteins (VLDL)
Low-density lipoproteins (LDL)
High density lipoproteins (HDL)
What form of fats is a VLDL? - ANSTriglyceride
What can accelerated ranges of triglyceride serum imply? - ANSCorondary artery disease
chance
What is the activity of the LDLs? - ANSthey deliver ldl cholesterol to the tissues
What is LDL manufactured from? - ANScholesterol and protein
What does an increased serum concentration of LDL-C suggest? - ANSCAD hazard
but relative risk depends on factors consisting of age, DM, and CKD
What is the feature of the HDLs? - ANSthey are "opposite cholesterol shipping"
Which of the serum lipoproteins returns extra ldl cholesterol from the tissues to the liver? -
ANSHDL (excessive density lipoproteins)
What happens to cholesterol in the liver? - ANSit is converted to ldl cholesterol-containing
steroids or bile for digestion
How does the HDLs impacts the LDL? - ANSHDL protects LDL from oxidation
What are some different capabilities of HDL? - ANSpreserves endothelial characteristic
promotes anti inflammatory and antithrombotic effects
What components make up HDLs? - ANSphospholipids and protein
What do LOW stages of HDL-C suggest? - ANSCAD threat
Elevated LDL is connected to continual heart sickness in individuals with what genetic disorder?
- ANShypercholesterolemia
,What is a reason of reduced LDL elimination - ANSdefective or reduced numbers of LDL
receptors
What can familiar hypercholesterolemia (FH) reason? - ANSblockage of arteries and heart
disease with out different risk elements
What genetic ailment causes bumps on the skin which can be composed of deposits of ldl
cholesterol derived from LDLs? - ANSHomozygous Familiary hypercholesterolemia
Name 6 modifiable hazard factors for Coronary artery ailment - ANSdylipemia
high blood pressure
cigarette smoking
DM and insulin resistance
obesity and sedentary way of life
atherogenic eating regimen (ldl cholesterol wealthy)
Name four non-modifiable hazard factors for coronary artery ailment - ANSadvanced age
male
postmenopausal women
own family history/genetics
Name 10 Novel Risk elements for CAD - ANShigh lipoprotein (dyslipidemia)
excessive LDL particle variety
small, dense LDL
increased markers for inflammation, ischemia and thrombosis
adipokines
Chronic kidney sickness
Air pollution and ionizing radioation
Medications
coronary artery calcification and carotid wall thickness
microbiome
What is the marker for irritation that may be a novel threat elements for CAD? - ANShigh touchy
C-reactive protein (hs-CRP)
What is hs-CRP? - ANSindirect degree of infection and plaque increase in blocked arteries
What is the marker for ischemia? - ANSTroponin I (tnI)
What is troponin I? - ANSIt is a marker used to discover coronary heart muscle harm throughout
acute coronary syndromes
What is the marker for thrombosis? - ANSHigh fibrinogen and protein C
, What is the time period used to explain a set of hormones released from fats cells? -
ANSadipokines
What are the 3 adipoknes? - ANSadiponectin
leptin
resistin
What are a few medicines that may contribute to CAD? - ANSNSAIDs
Anti rejection tablets/immunosuppressants
protease inhibitors
What happens while extended ranges of lips (particularly LDL cholesterol) accumulate in artery
walls? - ANSThere is a formation of plaque referred to as atherosclerosis
What is the time period used to explain while the arteries end up slender and stiff due to the
build up of fat and immune cells, forming locations that could block blood float? -
ANSAtherosclerosis!
Atherosclerosis is the main motive of what diseases? - ANSCoronary artery sickness
cardio-vascular disorder
What impact can plaque increase have at the arteries? - ANSit can harden and slender arteries,
in the end lowering blood drift to the heart
What takes place in CAD on the subject of atherosclerosis? - ANSCAD occurs while
artherosclerosis affects the coronary arteries.
What does the coronary artery characteristic to do? - ANSsupply oxygen-rich blood to the heart
muscle
What complications can narrowing or blockage of coronary arteries motive? - ANSchest ache
heart attack
What is the danger of CAD for LDL <100? - ANSoptimal - ideal, low risk
What is the risk of CAD for LDL 100-129? - ANSnear optimal
What is the risk of CAD for LDL 130-159? - ANSborderline
What is the risk of CAD for LDL 160-189? - ANSHigh
What is the risk of CAD for LDL >190? - ANSvery high
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