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NURS 8024 Pharm Test 3 Pt. 1 Exam Questions and Answers
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NURS 8024 Pharm Test 3 Pt. 1 Exam Questions and Answers
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NURS 8024 Pharm Test 3 Pt. 1 Exam Questions andAnswers
Tetracyclines, aminoglycosides, macrolides Correct Ans-Inhibitor of protein synthesis
MOA of fluoroquinolones Correct Ans-Inhibitor of nucleic acid function or synthesis
Sulfonamides and Trimethoprim Correct Ans-Inhibitors of metabolism
Beta-lactam antibiotics Correct Ans--inhibit cell wall synthesis
-bactericidal
-V common Rx
Beta-lactam pharmacokinetics Correct Ans--Time dependent killing
-short half life
-IV: 100% bioavailability
-PO: variable absorption rate and degree affected by FOOD
What Beta-lactams can penetrate the CSF? Correct Ans--3rd and 4th generation
cephalosporins, aztreonam, meropenem, (parenteral)
ADE of beta lactams Correct Ans--IgE mediated allergic reactions (hypersensitivity 3-10%)
-C DIFF
, NURS 8024 Pharm Test 3 Pt. 1 Exam Questions and
Answers
-Derm reactions
-neurologic
1st gen PCN Correct Ans-gram + cocci strep --> Yes!
spirochetes - syph --> very well!
Some use in community acquired PNA but must expand coverage in gram + to get staph
2nd gen PCN Correct Ans--increased activity against gram - bacilli
-Amoxicillin (better absorbed) and ampicillin
3rd Gen PCN Correct Ans--Broader spectrum w/ little gram+ coverage
-carbenicillin and ticarcillin
4th Gen PCN Correct Ans--some gram+ coverage
-Pipercillin: usually in combo w/ beta lactamase inhibitor
Narrow spectrum Correct Ans-act on a single or limited group of pathogens
Extended-spectrum Correct Ans-"Efficacy against large numbers of gram positive / gram
negative organisms"
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